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Development and regulatory application of microRNA biomarkers.
Krauskopf J, Verheijen M, Kleinjans JC, de Kok TM, Caiment F. Krauskopf J, et al. Among authors: caiment f. Biomark Med. 2015;9(11):1137-51. doi: 10.2217/bmm.15.50. Epub 2015 Oct 26. Biomark Med. 2015. PMID: 26502281 Review.
Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling.
Verheijen M, Schrooders Y, Gmuender H, Nudischer R, Clayton O, Hynes J, Niederer S, Cordes H, Kuepfer L, Kleinjans J, Caiment F. Verheijen M, et al. Among authors: caiment f. Toxicol Lett. 2018 Sep 15;294:184-192. doi: 10.1016/j.toxlet.2018.05.029. Epub 2018 May 24. Toxicol Lett. 2018. PMID: 29803840 Free article.
DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro.
Verheijen M, Lienhard M, Schrooders Y, Clayton O, Nudischer R, Boerno S, Timmermann B, Selevsek N, Schlapbach R, Gmuender H, Gotta S, Geraedts J, Herwig R, Kleinjans J, Caiment F. Verheijen M, et al. Among authors: caiment f. Sci Rep. 2019 Mar 15;9(1):4641. doi: 10.1038/s41598-019-40660-0. Sci Rep. 2019. PMID: 30874586 Free PMC article.
Towards the development of an omics data analysis framework.
Verheijen M, Tong W, Shi L, Gant TW, Seligman B, Caiment F. Verheijen M, et al. Among authors: caiment f. Regul Toxicol Pharmacol. 2020 Apr;112:104621. doi: 10.1016/j.yrtph.2020.104621. Epub 2020 Feb 19. Regul Toxicol Pharmacol. 2020. PMID: 32087354
Network integration and modelling of dynamic drug responses at multi-omics levels.
Selevsek N, Caiment F, Nudischer R, Gmuender H, Agarkova I, Atkinson FL, Bachmann I, Baier V, Barel G, Bauer C, Boerno S, Bosc N, Clayton O, Cordes H, Deeb S, Gotta S, Guye P, Hersey A, Hunter FMI, Kunz L, Lewalle A, Lienhard M, Merken J, Minguet J, Oliveira B, Pluess C, Sarkans U, Schrooders Y, Schuchhardt J, Smit I, Thiel C, Timmermann B, Verheijen M, Wittenberger T, Wolski W, Zerck A, Heymans S, Kuepfer L, Roth A, Schlapbach R, Niederer S, Herwig R, Kleinjans J. Selevsek N, et al. Among authors: caiment f. Commun Biol. 2020 Oct 15;3(1):573. doi: 10.1038/s42003-020-01302-8. Commun Biol. 2020. PMID: 33060801 Free PMC article.
iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples.
Verheijen MCT, Krauskopf J, Caiment F, Nazaruk M, Wen QF, van Herwijnen MHM, Hauser DA, Gajjar M, Verfaillie C, Vermeiren Y, De Deyn PP, Wittens MMJ, Sieben A, Engelborghs S, Dejonckheere W, Princen K, Griffioen G, Roggen EL, Briedé JJ. Verheijen MCT, et al. Among authors: caiment f. Toxicol Lett. 2022 Mar 1;356:89-99. doi: 10.1016/j.toxlet.2021.12.009. Epub 2021 Dec 15. Toxicol Lett. 2022. PMID: 34921933 Free article.
R-ODAF: Omics data analysis framework for regulatory application.
Verheijen MC, Meier MJ, Asensio JO, Gant TW, Tong W, Yauk CL, Caiment F. Verheijen MC, et al. Among authors: caiment f. Regul Toxicol Pharmacol. 2022 Jun;131:105143. doi: 10.1016/j.yrtph.2022.105143. Epub 2022 Mar 3. Regul Toxicol Pharmacol. 2022. PMID: 35247516 Free article.
60 results