Ruggero D - Search Results

1

Localization of a TORC1-eIF4F translation complex during CD8⁺ T cell activation drives divergent cell fate.

Liedmann S, Liu X, Guy CS, Crawford JC, Rodriguez DA, Kuzuoğlu-Öztürk D, Guo A, Verbist KC, Temirov J, Chen MJ, Ruggero D, Zhang H, Thomas PG, Green DR. Liedmann S, et al. Among authors: ruggero d. Mol Cell. 2022 Jul 7;82(13):2401-2414.e9. doi: 10.1016/j.molcel.2022.04.016. Epub 2022 May 20. Mol Cell. 2022. PMID: 35597236 Free PMC article.

2

The translational landscape of the mammalian cell cycle.

Stumpf CR, Moreno MV, Olshen AB, Taylor BS, Ruggero D. Stumpf CR, et al. Among authors: ruggero d. Mol Cell. 2013 Nov 21;52(4):574-82. doi: 10.1016/j.molcel.2013.09.018. Epub 2013 Oct 10. Mol Cell. 2013. PMID: 24120665 Free PMC article.

3

Targeting the eIF4F translation initiation complex: a critical nexus for cancer development.

Pelletier J, Graff J, Ruggero D, Sonenberg N. Pelletier J, et al. Among authors: ruggero d. Cancer Res. 2015 Jan 15;75(2):250-63. doi: 10.1158/0008-5472.CAN-14-2789. Cancer Res. 2015. PMID: 25593033 Free PMC article. Review.

4

A Translation Tuning HuDdle for Neurons.

McMahon M, Ruggero D. McMahon M, et al. Among authors: ruggero d. Mol Cell. 2018 Jul 19;71(2):195-196. doi: 10.1016/j.molcel.2018.07.007. Mol Cell. 2018. PMID: 30028999 Free article.

5

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.

Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. Kuzuoglu-Ozturk D, et al. Among authors: ruggero d. Cell Rep. 2021 Jun 29;35(13):109321. doi: 10.1016/j.celrep.2021.109321. Cell Rep. 2021. PMID: 34192540 Free PMC article.

6

Protein synthesis control in cancer: selectivity and therapeutic targeting.

Kovalski JR, Kuzuoglu-Ozturk D, Ruggero D. Kovalski JR, et al. Among authors: ruggero d. EMBO J. 2022 Apr 19;41(8):e109823. doi: 10.15252/embj.2021109823. Epub 2022 Mar 22. EMBO J. 2022. PMID: 35315941 Free PMC article. Review.

7

N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma.

Kuzuoglu-Ozturk D, Aksoy O, Schmidt C, Lea R, Larson JD, Phelps RRL, Nasholm N, Holt M, Contreras A, Huang M, Wong-Michalak S, Shao H, Wechsler-Reya R, Phillips JJ, Gestwicki JE, Ruggero D, Weiss WA. Kuzuoglu-Ozturk D, et al. Among authors: ruggero d. Cancer Res. 2023 Jan 4;83(1):130-140. doi: 10.1158/0008-5472.CAN-22-0945. Cancer Res. 2023. PMID: 36264168 Free PMC article.

8

Evolutionarily divergent mTOR remodels translatome for tissue regeneration.

Zhulyn O, Rosenblatt HD, Shokat L, Dai S, Kuzuoglu-Öztürk D, Zhang Z, Ruggero D, Shokat KM, Barna M. Zhulyn O, et al. Among authors: ruggero d. Nature. 2023 Aug;620(7972):163-171. doi: 10.1038/s41586-023-06365-1. Epub 2023 Jul 26. Nature. 2023. PMID: 37495694

9

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis.

Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi PP. Zhong S, et al. Among authors: ruggero d. J Exp Med. 2000 Feb 21;191(4):631-40. doi: 10.1084/jem.191.4.631. J Exp Med. 2000. PMID: 10684855 Free PMC article.

10

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.

Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM. Feldman ME, et al. Among authors: ruggero d. PLoS Biol. 2009 Feb 10;7(2):e38. doi: 10.1371/journal.pbio.1000038. PLoS Biol. 2009. PMID: 19209957 Free PMC article.

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