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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.
Durbin AD, Wang T, Wimalasena VK, Zimmerman MW, Li D, Dharia NV, Mariani L, Shendy NAM, Nance S, Patel AG, Shao Y, Mundada M, Maxham L, Park PMC, Sigua LH, Morita K, Conway AS, Robichaud AL, Perez-Atayde AR, Bikowitz MJ, Quinn TR, Wiest O, Easton J, Schönbrunn E, Bulyk ML, Abraham BJ, Stegmaier K, Look AT, Qi J. Durbin AD, et al. Among authors: shendy nam. Cancer Discov. 2022 Mar 1;12(3):730-751. doi: 10.1158/2159-8290.CD-21-0385. Cancer Discov. 2022. PMID: 34772733 Free PMC article.
GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells.
Raghu D, Mobley RJ, Shendy NAM, Perry CH, Abell AN. Raghu D, et al. Among authors: shendy nam. Cell Rep. 2019 Mar 26;26(13):3684-3697.e7. doi: 10.1016/j.celrep.2019.02.093. Cell Rep. 2019. PMID: 30917321 Free PMC article.
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Shendy NAM, Bikowitz M, Sigua LH, Zhang Y, Mercier A, Khashana Y, Nance S, Liu Q, Delahunty IM, Robinson S, Goel V, Rees MG, Ronan MA, Wang T, Kocak M, Roth JA, Wang Y, Freeman BB, Orr BA, Abraham BJ, Roussel MF, Schonbrunn E, Qi J, Durbin AD. Shendy NAM, et al. Nat Commun. 2024 Apr 25;15(1):3483. doi: 10.1038/s41467-024-47102-0. Nat Commun. 2024. PMID: 38664416 Free PMC article.
Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma.
Abu-Zaid A, Fang J, Jin H, Singh S, Pichavaram P, Wu Q, Tillman H, Janke L, Rosikiewicz W, Xu B, Van De Velde LA, Guo Y, Li Y, Shendy NAM, Delahunty IM, Rankovic Z, Chen T, Chen X, Freeman KW, Hatley ME, Durbin AD, Murray PJ, Murphy AJ, Thomas PG, Davidoff AM, Yang J. Abu-Zaid A, et al. Among authors: shendy nam. Cell Rep Med. 2024 Mar 19;5(3):101468. doi: 10.1016/j.xcrm.2024.101468. Cell Rep Med. 2024. PMID: 38508144 Free PMC article.
PRMT5 orchestrates EGFR and AKT networks to activate NFκB and promote EMT.
Huang L, Ravi M, Zhang XO, Verdejo-Torres O, Shendy NAM, Nezhady MAM, Gopalan S, Wang G, Durbin AD, Fazzio TG, Wu Q. Huang L, et al. Among authors: shendy nam. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574104. doi: 10.1101/2024.01.03.574104. bioRxiv. 2024. PMID: 38260418 Free PMC article. Preprint.