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Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro-4H-[1,2,3]triazolo[4,5-c]quinolin-4-one (CQ211) as a Highly Potent and Selective RIOK2 Inhibitor.
Ouyang Y, Si H, Zhu C, Zhong L, Ma H, Li Z, Xiong H, Liu T, Liu Z, Zhang Z, Zhang ZM, Cai Q. Ouyang Y, et al. Among authors: liu z, liu t. J Med Chem. 2022 Jun 9;65(11):7833-7842. doi: 10.1021/acs.jmedchem.2c00271. Epub 2022 May 18. J Med Chem. 2022. PMID: 35584513
Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.
Huang M, Chen M, Qi M, Ye G, Pan J, Shi C, Yang Y, Zhao L, Mo X, Zhang Y, Li Y, Zhong J, Lu W, Li X, Zhang J, Lin J, Luo L, Liu T, Tang PM, Hong A, Cao Y, Ye W, Zhang D. Huang M, et al. Among authors: liu t. J Extracell Vesicles. 2021 May;10(7):e12096. doi: 10.1002/jev2.12096. Epub 2021 May 21. J Extracell Vesicles. 2021. PMID: 34035882 Free PMC article.
Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models.
Qi M, Fan S, Huang M, Pan J, Li Y, Miao Q, Lyu W, Li X, Deng L, Qiu S, Liu T, Deng W, Chu X, Jiang C, He W, Xia L, Yang Y, Hong J, Qi Q, Yin W, Liu X, Shi C, Chen M, Ye W, Zhang D. Qi M, et al. Among authors: liu x, liu t. J Clin Invest. 2022 Oct 3;132(19):e157399. doi: 10.1172/JCI157399. J Clin Invest. 2022. PMID: 35951441 Free PMC article.
Chronic inflammation, cancer development and immunotherapy.
Wen Y, Zhu Y, Zhang C, Yang X, Gao Y, Li M, Yang H, Liu T, Tang H. Wen Y, et al. Among authors: liu t. Front Pharmacol. 2022 Oct 14;13:1040163. doi: 10.3389/fphar.2022.1040163. eCollection 2022. Front Pharmacol. 2022. PMID: 36313280 Free PMC article. Review.
Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation.
Yang Z, Shi J, Xie J, Wang Y, Sun J, Liu T, Zhao Y, Zhao X, Wang X, Ma Y, Malkoc V, Chiang C, Deng W, Chen Y, Fu Y, Kwak KJ, Fan Y, Kang C, Yin C, Rhee J, Bertani P, Otero J, Lu W, Yun K, Lee AS, Jiang W, Teng L, Kim BYS, Lee LJ. Yang Z, et al. Among authors: liu t. Nat Biomed Eng. 2020 Jan;4(1):69-83. doi: 10.1038/s41551-019-0485-1. Epub 2019 Dec 16. Nat Biomed Eng. 2020. PMID: 31844155 Free PMC article.
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