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Cation Chloride Cotransporter NKCC1 Operates through a Rocking-Bundle Mechanism.
Ruiz Munevar MJ, Rizzi V, Portioli C, Vidossich P, Cao E, Parrinello M, Cancedda L, De Vivo M. Ruiz Munevar MJ, et al. Among authors: portioli c. J Am Chem Soc. 2024 Jan 10;146(1):552-566. doi: 10.1021/jacs.3c10258. Epub 2023 Dec 25. J Am Chem Soc. 2024. PMID: 38146212 Free PMC article.
Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome.
Borgogno M, Savardi A, Manigrasso J, Turci A, Portioli C, Ottonello G, Bertozzi SM, Armirotti A, Contestabile A, Cancedda L, De Vivo M. Borgogno M, et al. Among authors: portioli c. J Med Chem. 2021 Jul 22;64(14):10203-10229. doi: 10.1021/acs.jmedchem.1c00603. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34137257 Free PMC article.
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