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Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.
Morris JC, Weiner M, Xiong C, Beckett L, Coble D, Saito N, Aisen PS, Allegri R, Benzinger TLS, Berman SB, Cairns NJ, Carrillo MC, Chui HC, Chhatwal JP, Cruchaga C, Fagan AM, Farlow M, Fox NC, Ghetti B, Goate AM, Gordon BA, Graff-Radford N, Day GS, Hassenstab J, Ikeuchi T, Jack CR, Jagust WJ, Jucker M, Levin J, Massoumzadeh P, Masters CL, Martins R, McDade E, Mori H, Noble JM, Petersen RC, Ringman JM, Salloway S, Saykin AJ, Schofield PR, Shaw LM, Toga AW, Trojanowski JQ, Vöglein J, Weninger S, Bateman RJ, Buckles VD. Morris JC, et al. Among authors: aisen ps. Brain. 2022 Oct 21;145(10):3594-3607. doi: 10.1093/brain/awac181. Brain. 2022. PMID: 35580594 Free PMC article.
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR Jr, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Among authors: aisen ps. Arch Neurol. 2004 Jan;61(1):59-66. doi: 10.1001/archneur.61.1.59. Arch Neurol. 2004. PMID: 14732621 Clinical Trial.
Multi-modal imaging predicts memory performance in normal aging and cognitive decline.
Walhovd KB, Fjell AM, Dale AM, McEvoy LK, Brewer J, Karow DS, Salmon DP, Fennema-Notestine C; Alzheimer's Disease Neuroimaging Initiative. Walhovd KB, et al. Neurobiol Aging. 2010 Jul;31(7):1107-21. doi: 10.1016/j.neurobiolaging.2008.08.013. Epub 2008 Oct 5. Neurobiol Aging. 2010. PMID: 18838195 Free PMC article.
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.
Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, Blennow K, Soares H, Simon A, Lewczuk P, Dean R, Siemers E, Potter W, Lee VM, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative. Shaw LM, et al. Among authors: aisen ps. Ann Neurol. 2009 Apr;65(4):403-13. doi: 10.1002/ana.21610. Ann Neurol. 2009. PMID: 19296504 Free PMC article.
627 results