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Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis.
Julià A, Gómez A, López-Lasanta M, Blanco F, Erra A, Fernández-Nebro A, Mas AJ, Pérez-García C, Vivar MLG, Sánchez-Fernández S, Alperi-López M, Sanmartí R, Ortiz AM, Fernandez-Cid CM, Díaz-Torné C, Moreno E, Li T, Martínez-Mateu SH, Absher DM, Myers RM, Molina JT, Marsal S. Julià A, et al. Among authors: li t. EBioMedicine. 2022 Jun;80:104053. doi: 10.1016/j.ebiom.2022.104053. Epub 2022 May 13. EBioMedicine. 2022. PMID: 35576644 Free PMC article.
Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis.
Rodríguez-Ubreva J, de la Calle-Fabregat C, Li T, Ciudad L, Ballestar ML, Català-Moll F, Morante-Palacios O, Garcia-Gomez A, Celis R, Humby F, Nerviani A, Martin J, Pitzalis C, Cañete JD, Ballestar E. Rodríguez-Ubreva J, et al. Among authors: li t. Ann Rheum Dis. 2019 Nov;78(11):1505-1516. doi: 10.1136/annrheumdis-2019-215355. Epub 2019 Aug 1. Ann Rheum Dis. 2019. PMID: 31371305
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Garcia-Gomez A, Li T, de la Calle-Fabregat C, Rodríguez-Ubreva J, Ciudad L, Català-Moll F, Godoy-Tena G, Martín-Sánchez M, San-Segundo L, Muntión S, Morales X, Ortiz-de-Solórzano C, Oyarzabal J, San José-Enériz E, Esteller M, Agirre X, Prosper F, Garayoa M, Ballestar E. Garcia-Gomez A, et al. Among authors: li t. Nat Commun. 2021 Jan 18;12(1):421. doi: 10.1038/s41467-020-20715-x. Nat Commun. 2021. PMID: 33462210 Free PMC article.
Genomic Risk Score impact on susceptibility to systemic sclerosis.
Bossini-Castillo L, Villanueva-Martin G, Kerick M, Acosta-Herrera M, López-Isac E, Simeón CP, Ortego-Centeno N, Assassi S; International SSc Group; Australian Scleroderma Interest Group (ASIG); PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry study group; Hunzelmann N, Gabrielli A, de Vries-Bouwstra JK, Allanore Y, Fonseca C, Denton CP, Radstake TR, Alarcón-Riquelme ME, Beretta L, Mayes MD, Martin J. Bossini-Castillo L, et al. Ann Rheum Dis. 2021 Jan;80(1):118-127. doi: 10.1136/annrheumdis-2020-218558. Epub 2020 Oct 1. Ann Rheum Dis. 2021. PMID: 33004331 Free article.
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases.
Barturen G, Babaei S, Català-Moll F, Martínez-Bueno M, Makowska Z, Martorell-Marugán J, Carmona-Sáez P, Toro-Domínguez D, Carnero-Montoro E, Teruel M, Kerick M, Acosta-Herrera M, Le Lann L, Jamin C, Rodríguez-Ubreva J, García-Gómez A, Kageyama J, Buttgereit A, Hayat S, Mueller J, Lesche R, Hernandez-Fuentes M, Juarez M, Rowley T, White I, Marañón C, Gomes Anjos T, Varela N, Aguilar-Quesada R, Garrancho FJ, López-Berrio A, Rodriguez Maresca M, Navarro-Linares H, Almeida I, Azevedo N, Brandão M, Campar A, Faria R, Farinha F, Marinho A, Neves E, Tavares A, Vasconcelos C, Trombetta E, Montanelli G, Vigone B, Alvarez-Errico D, Li T, Thiagaran D, Blanco Alonso R, Corrales Martínez A, Genre F, López Mejías R, Gonzalez-Gay MA, Remuzgo S, Ubilla Garcia B, Cervera R, Espinosa G, Rodríguez-Pintó I, De Langhe E, Cremer J, Lories R, Belz D, Hunzelmann N, Baerlecken N, Kniesch K, Witte T, Lehner M, Stummvoll G, Zauner M, Aguirre-Zamorano MA, Barbarroja N, Castro-Villegas MC, Collantes-Estevez E, de Ramon E, Díaz Quintero I, Escudero-Contreras A, Fernández Roldán MC, Jiménez Gómez Y, Jiménez Moleón I, Lopez-Pedrera R, Ortega-Castro R, Ortego N, Raya E, Artusi C, Gerosa M, Meroni PL, Schio… See abstract for full author list ➔ Barturen G, et al. Among authors: li t. Arthritis Rheumatol. 2021 Jun;73(6):1073-1085. doi: 10.1002/art.41610. Epub 2021 Apr 26. Arthritis Rheumatol. 2021. PMID: 33497037 Free article.
Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction.
Català-Moll F, Ferreté-Bonastre AG, Li T, Weichenhan D, Lutsik P, Ciudad L, Álvarez-Prado ÁF, Rodríguez-Ubreva J, Klemann C, Speckmann C, Vilas-Zornoza A, Abolhassani H, Martínez-Gallo M, Dieli-Crimi R, Rivière JG, Martín-Nalda A, Colobran R, Soler-Palacín P, Kracker S, Hammarström L, Prosper F, Durandy A, Grimbacher B, Plass C, Ballestar E. Català-Moll F, et al. Among authors: li t. Nucleic Acids Res. 2021 May 21;49(9):5057-5073. doi: 10.1093/nar/gkab322. Nucleic Acids Res. 2021. PMID: 33950194 Free PMC article.
Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci.
Li T, Ortiz-Fernández L, Andrés-León E, Ciudad L, Javierre BM, López-Isac E, Guillén-Del-Castillo A, Simeón-Aznar CP, Ballestar E, Martin J. Li T, et al. Genome Med. 2020 Sep 25;12(1):81. doi: 10.1186/s13073-020-00779-6. Genome Med. 2020. PMID: 32977850 Free PMC article.
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