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Activation of adenosine A2A or A2B receptors causes hypothermia in mice.
Carlin JL, Jain S, Duroux R, Suresh RR, Xiao C, Auchampach JA, Jacobson KA, Gavrilova O, Reitman ML. Carlin JL, et al. Among authors: suresh rr. Neuropharmacology. 2018 Sep 1;139:268-278. doi: 10.1016/j.neuropharm.2018.02.035. Epub 2018 Mar 13. Neuropharmacology. 2018. PMID: 29548686 Free PMC article.
Design and in vivo activity of A3 adenosine receptor agonist prodrugs.
Suresh RR, Jain S, Chen Z, Tosh DK, Ma Y, Podszun MC, Rotman Y, Salvemini D, Jacobson KA. Suresh RR, et al. Purinergic Signal. 2020 Sep;16(3):367-377. doi: 10.1007/s11302-020-09715-0. Epub 2020 Jul 27. Purinergic Signal. 2020. PMID: 32720036 Free PMC article.
Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology.
Liston TE, Hinz S, Müller CE, Holstein DM, Wendling J, Melton RJ, Campbell M, Korinek WS, Suresh RR, Sethre-Hofstad DA, Gao ZG, Tosh DK, Jacobson KA, Lechleiter JD. Liston TE, et al. Among authors: suresh rr. Purinergic Signal. 2020 Dec;16(4):543-559. doi: 10.1007/s11302-020-09732-z. Epub 2020 Oct 31. Purinergic Signal. 2020. PMID: 33129204 Free PMC article.
Ligand design by targeting a binding site water.
Matricon P, Suresh RR, Gao ZG, Panel N, Jacobson KA, Carlsson J. Matricon P, et al. Among authors: suresh rr. Chem Sci. 2020 Nov 19;12(3):960-968. doi: 10.1039/d0sc04938g. Chem Sci. 2020. PMID: 34163862 Free PMC article.
23 results