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Page 1
Defining Environmental Health Literacy.
Lindsey M, Chen SR, Ben R, Manoogian M, Spradlin J. Lindsey M, et al. Among authors: spradlin j. Int J Environ Res Public Health. 2021 Nov 5;18(21):11626. doi: 10.3390/ijerph182111626. Int J Environ Res Public Health. 2021. PMID: 34770140 Free PMC article.
Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors.
Moon P, Zammit CM, Shao Q, Dovala D, Boike L, Henning NJ, Knapp M, Spradlin JN, Ward CC, Wolleb H, Fuller D, Blake G, Murphy JP, Wang F, Lu Y, Moquin SA, Tandeske L, Hesse MJ, McKenna JM, Tallarico JA, Schirle M, Toste FD, Nomura DK. Moon P, et al. Among authors: spradlin jn. Chembiochem. 2023 Jun 1;24(11):e202300116. doi: 10.1002/cbic.202300116. Epub 2023 May 3. Chembiochem. 2023. PMID: 37069799
De novo Design of SARS-CoV-2 Main Protease Inhibitors.
Fischer C, Vepřek NA, Peitsinis Z, Rühmann KP, Yang C, Spradlin JN, Dovala D, Nomura DK, Zhang Y, Trauner D. Fischer C, et al. Among authors: spradlin jn. Synlett. 2021 Aug;33(5):458-463. doi: 10.1055/a-1582-0243. Epub 2021 Aug 10. Synlett. 2021. PMID: 35282568 Free PMC article.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, Frank AO, Fuller D, Estes AR, Randal KL, Panidapu A, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Henning NJ, et al. Among authors: spradlin jn. Nat Chem Biol. 2022 Apr;18(4):412-421. doi: 10.1038/s41589-022-00971-2. Epub 2022 Feb 24. Nat Chem Biol. 2022. PMID: 35210618 Free PMC article.
Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2.
Biering SB, Van Dis E, Wehri E, Yamashiro LH, Nguyenla X, Dugast-Darzacq C, Graham TGW, Stroumza JR, Golovkine GR, Roberts AW, Fines DM, Spradlin JN, Ward CC, Bajaj T, Dovala D, Schulze-Gamen U, Bajaj R, Fox DM, Ott M, Murthy N, Nomura DK, Schaletzky J, Stanley SA. Biering SB, et al. Among authors: spradlin jn. ACS Infect Dis. 2021 Aug 13;7(8):2337-2351. doi: 10.1021/acsinfecdis.1c00017. Epub 2021 Jun 15. ACS Infect Dis. 2021. PMID: 34129317
Reimagining Druggability Using Chemoproteomic Platforms.
Spradlin JN, Zhang E, Nomura DK. Spradlin JN, et al. Acc Chem Res. 2021 Apr 6;54(7):1801-1813. doi: 10.1021/acs.accounts.1c00065. Epub 2021 Mar 18. Acc Chem Res. 2021. PMID: 33733731 Review.
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