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Genetics, pathobiology and therapeutic opportunities of polycystic liver disease.
Nat Rev Gastroenterol Hepatol. 2022 Sep;19(9):585-604. doi: 10.1038/s41575-022-00617-7. Epub 2022 May 13.
Nat Rev Gastroenterol Hepatol. 2022.
PMID: 35562534
Review.
Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease.
Caballero-Camino FJ, Rivilla I, Herraez E, Briz O, Santos-Laso A, Izquierdo-Sanchez L, Lee-Law PY, Rodrigues PM, Munoz-Garrido P, Jin S, Peixoto E, Richard S, Gradilone SA, Perugorria MJ, Esteller M, Bujanda L, Marin JJG, Banales JM, Cossío FP.
Caballero-Camino FJ, et al.
Hepatology. 2021 Jan;73(1):186-203. doi: 10.1002/hep.31216. Epub 2020 Sep 22.
Hepatology. 2021.
PMID: 32145077
Free PMC article.
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Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets.
Santos-Laso A, Izquierdo-Sanchez L, Rodrigues PM, Huang BQ, Azkargorta M, Lapitz A, Munoz-Garrido P, Arbelaiz A, Caballero-Camino FJ, Fernández-Barrena MG, Jimenez-Agüero R, Argemi J, Aragon T, Elortza F, Marzioni M, Drenth JPH, LaRusso NF, Bujanda L, Perugorria MJ, Banales JM.
Santos-Laso A, et al. Among authors: caballero camino fj.
Liver Int. 2020 Jul;40(7):1670-1685. doi: 10.1111/liv.14485. Epub 2020 May 6.
Liver Int. 2020.
PMID: 32378324
Free PMC article.
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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models.
Lee-Law PY, Olaizola P, Caballero-Camino FJ, Izquierdo-Sanchez L, Rodrigues PM, Santos-Laso A, Azkargorta M, Elortza F, Martinez-Chantar ML, Perugorria MJ, Aspichueta P, Marzioni M, LaRusso NF, Bujanda L, Drenth JPH, Banales JM.
Lee-Law PY, et al. Among authors: caballero camino fj.
J Hepatol. 2021 Feb;74(2):394-406. doi: 10.1016/j.jhep.2020.09.010. Epub 2020 Sep 17.
J Hepatol. 2021.
PMID: 32950589
Free PMC article.
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Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease.
Lee-Law PY, Olaizola P, Caballero-Camino FJ, Izquierdo-Sanchez L, Rodrigues PM, Perugorria MJ, Azkargorta M, Elortza F, Martinez-Chantar ML, Aspichueta P, Marzioni M, Bujanda L, Drenth JPH, Banales JM.
Lee-Law PY, et al. Among authors: caballero camino fj.
United European Gastroenterol J. 2021 Sep;9(7):848-859. doi: 10.1002/ueg2.12126. Epub 2021 Jul 26.
United European Gastroenterol J. 2021.
PMID: 34310849
Free PMC article.
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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models.
Olaizola P, Lee-Law PY, Fernandez-Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, O'Rourke CJ, Caballero-Camino FJ, Olaizola I, Macias RIR, Marin JJG, Serrano-Maciá M, Martinez-Chantar ML, Avila MA, Aspichueta P, Calvisi DF, Evert M, Fabris L, Castro RE, Elortza F, Andersen JB, Bujanda L, Rodrigues PM, Perugorria MJ, Banales JM.
Olaizola P, et al. Among authors: caballero camino fj.
J Hepatol. 2022 Jul;77(1):177-190. doi: 10.1016/j.jhep.2022.02.007. Epub 2022 Feb 23.
J Hepatol. 2022.
PMID: 35217064
Free article.
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM.
Caballero-Camino FJ, et al.
Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1.
Hepatology. 2023.
PMID: 36999529
Free PMC article.
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Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma.
Lapitz A, Azkargorta M, Milkiewicz P, Olaizola P, Zhuravleva E, Grimsrud MM, Schramm C, Arbelaiz A, O'Rourke CJ, La Casta A, Milkiewicz M, Pastor T, Vesterhus M, Jimenez-Agüero R, Dill MT, Lamarca A, Valle JW, Macias RIR, Izquierdo-Sanchez L, Pérez Castaño Y, Caballero-Camino FJ, Riaño I, Krawczyk M, Ibarra C, Bustamante J, Nova-Camacho LM, Falcon-Perez JM, Elortza F, Perugorria MJ, Andersen JB, Bujanda L, Karlsen TH, Folseraas T, Rodrigues PM, Banales JM.
Lapitz A, et al. Among authors: caballero camino fj.
J Hepatol. 2023 Jul;79(1):93-108. doi: 10.1016/j.jhep.2023.02.027. Epub 2023 Mar 1.
J Hepatol. 2023.
PMID: 36868481
Free PMC article.
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