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Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage.
Molendijk J, Kolka CM, Cairns H, Brosda S, Mohamed A, Shah AK, Brown I, Hodson MP, Hennessy T, Liu G, Stoll T, Richards RS, Gartside M, Patel K, Clemons NJ, Phillips WA, Barbour A, Westerhuis JA, Hill MM. Molendijk J, et al. Among authors: patel k. Clin Transl Med. 2022 May;12(5):e810. doi: 10.1002/ctm2.810. Clin Transl Med. 2022. PMID: 35560527 Free PMC article.
Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma.
Krause L, Nones K, Loffler KA, Nancarrow D, Oey H, Tang YH, Wayte NJ, Patch AM, Patel K, Brosda S, Manning S, Lampe G, Clouston A, Thomas J, Stoye J, Hussey DJ, Watson DI, Lord RV, Phillips WA, Gotley D, Smithers BM, Whiteman DC, Hayward NK, Grimmond SM, Waddell N, Barbour AP. Krause L, et al. Among authors: patel k. Carcinogenesis. 2016 Apr;37(4):356-65. doi: 10.1093/carcin/bgw018. Epub 2016 Feb 10. Carcinogenesis. 2016. PMID: 26905591 Free PMC article.
Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples.
Newell F, Patel K, Gartside M, Krause L, Brosda S, Aoude LG, Loffler KA, Bonazzi VF, Patch AM, Kazakoff SH, Holmes O, Xu Q, Wood S, Leonard C, Lampe G, Lord RV, Whiteman DC, Pearson JV, Nones K, Waddell N, Barbour AP. Newell F, et al. Among authors: patel k. BMC Med Genomics. 2019 Feb 4;12(1):31. doi: 10.1186/s12920-019-0476-9. BMC Med Genomics. 2019. PMID: 30717762 Free PMC article.
Radiomics Biomarkers Correlate with CD8 Expression and Predict Immune Signatures in Melanoma Patients.
Aoude LG, Wong BZY, Bonazzi VF, Brosda S, Walters SB, Koufariotis LT, Naeini MM, Pearson JV, Oey H, Patel K, Bradford JJ, Bloxham CJ, Atkinson V, Law P, Strutton G, Bayley G, Yang S, Smithers BM, Waddell N, Miles K, Barbour AP. Aoude LG, et al. Among authors: patel k. Mol Cancer Res. 2021 Jun;19(6):950-956. doi: 10.1158/1541-7786.MCR-20-1038. Epub 2021 Apr 2. Mol Cancer Res. 2021. PMID: 33811161
ctDNA as a biomarker of progression in oesophageal adenocarcinoma.
Bonazzi VF, Aoude LG, Brosda S, Lonie JM, Patel K, Bradford JJ, Koufariotis LT, Wood S, Smithers BM, Waddell N, Barbour AP. Bonazzi VF, et al. Among authors: patel k. ESMO Open. 2022 Jun;7(3):100452. doi: 10.1016/j.esmoop.2022.100452. Epub 2022 Mar 23. ESMO Open. 2022. PMID: 35798469 Free PMC article.
Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy.
M Naeini M, Newell F, Aoude LG, Bonazzi VF, Patel K, Lampe G, Koufariotis LT, Lakis V, Addala V, Kondrashova O, Johnston RL, Sharma S, Brosda S, Holmes O, Leonard C, Wood S, Xu Q, Thomas J, Walpole E, Tao Mai G, Ackland SP, Martin J, Burge M, Finch R, Karapetis CS, Shannon J, Nott L, Bohmer R, Wilson K, Barnes E, Zalcberg JR, Mark Smithers B, Simes J, Price T, Gebski V, Nones K, Watson DI, Pearson JV, Barbour AP, Waddell N. M Naeini M, et al. Among authors: patel k. Nat Commun. 2023 May 31;14(1):3155. doi: 10.1038/s41467-023-38891-x. Nat Commun. 2023. PMID: 37258531 Free PMC article.
C-reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients.
Bonazzi VF, Aoude LG, Brosda S, Bradford JJ, Lonie JM, Loffler KA, Gartside MG, Patel K, Mukhopadhyay P, Keane C, Gebski V, Kench JG, Goldstein D, Waddell N, Barbour AP; Australasian Gastro-Intestinal Trials Group (AGITG) GAP investigators. Bonazzi VF, et al. Among authors: patel k. Asia Pac J Clin Oncol. 2023 Jul 6. doi: 10.1111/ajco.13993. Online ahead of print. Asia Pac J Clin Oncol. 2023. PMID: 37415393
The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy - results from the AGITG DOCTOR trial and the cancer evolution biobank.
Lonie JM, Brosda S, Bonazzi VF, Aoude LG, Patel K, Brown I, Sharma S, Lampe G, Addala V, Koufariotis LT, Wood S, Waddell N, Dolcetti R, Barbour AP. Lonie JM, et al. Among authors: patel k. Front Immunol. 2023 Oct 12;14:1220129. doi: 10.3389/fimmu.2023.1220129. eCollection 2023. Front Immunol. 2023. PMID: 37965317 Free PMC article.
8,351 results