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Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage.
Molendijk J, Kolka CM, Cairns H, Brosda S, Mohamed A, Shah AK, Brown I, Hodson MP, Hennessy T, Liu G, Stoll T, Richards RS, Gartside M, Patel K, Clemons NJ, Phillips WA, Barbour A, Westerhuis JA, Hill MM. Molendijk J, et al. Among authors: hodson mp. Clin Transl Med. 2022 May;12(5):e810. doi: 10.1002/ctm2.810. Clin Transl Med. 2022. PMID: 35560527 Free PMC article.
Triheptanoin alters [U-13C6]-glucose incorporation into glycolytic intermediates and increases TCA cycling by normalizing the activities of pyruvate dehydrogenase and oxoglutarate dehydrogenase in a chronic epilepsy mouse model.
McDonald T, Hodson MP, Bederman I, Puchowicz M, Borges K. McDonald T, et al. Among authors: hodson mp. J Cereb Blood Flow Metab. 2020 Mar;40(3):678-691. doi: 10.1177/0271678X19837380. Epub 2019 Mar 19. J Cereb Blood Flow Metab. 2020. PMID: 30890077 Free PMC article.
Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.
Zhuang A, Yap FY, Bruce C, Leung C, Plan MR, Sullivan MA, Herath C, McCarthy D, Sourris KC, Kantharidis P, Coughlan MT, Febbraio MA, Hodson MP, Watt MJ, Angus P, Schulz BL, Forbes JM. Zhuang A, et al. Among authors: hodson mp. Sci Rep. 2017 Sep 25;7(1):12292. doi: 10.1038/s41598-017-12548-4. Sci Rep. 2017. PMID: 28947796 Free PMC article.
Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.
Das Gupta K, Shakespear MR, Curson JEB, Murthy AMV, Iyer A, Hodson MP, Ramnath D, Tillu VA, von Pein JB, Reid RC, Tunny K, Hohenhaus DM, Moradi SV, Kelly GM, Kobayashi T, Gunter JH, Stevenson AJ, Xu W, Luo L, Jones A, Johnston WA, Blumenthal A, Alexandrov K, Collins BM, Stow JL, Fairlie DP, Sweet MJ. Das Gupta K, et al. Among authors: hodson mp. Cell Rep. 2020 Feb 25;30(8):2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007. Cell Rep. 2020. PMID: 32101747 Free article.
Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer.
Wang Q, Ye J, Fang D, Lv L, Wu W, Shi D, Li Y, Yang L, Bian X, Wu J, Jiang X, Wang K, Wang Q, Hodson MP, Thibaut LM, Ho JWK, Giannoulatou E, Li L. Wang Q, et al. Among authors: hodson mp. BMC Microbiol. 2020 Apr 23;20(Suppl 1):83. doi: 10.1186/s12866-020-01762-2. BMC Microbiol. 2020. PMID: 32321427 Free PMC article.
61 results