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Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage.
Molendijk J, Kolka CM, Cairns H, Brosda S, Mohamed A, Shah AK, Brown I, Hodson MP, Hennessy T, Liu G, Stoll T, Richards RS, Gartside M, Patel K, Clemons NJ, Phillips WA, Barbour A, Westerhuis JA, Hill MM. Molendijk J, et al. Among authors: gartside m. Clin Transl Med. 2022 May;12(5):e810. doi: 10.1002/ctm2.810. Clin Transl Med. 2022. PMID: 35560527 Free PMC article.
Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples.
Newell F, Patel K, Gartside M, Krause L, Brosda S, Aoude LG, Loffler KA, Bonazzi VF, Patch AM, Kazakoff SH, Holmes O, Xu Q, Wood S, Leonard C, Lampe G, Lord RV, Whiteman DC, Pearson JV, Nones K, Waddell N, Barbour AP. Newell F, et al. Among authors: gartside m. BMC Med Genomics. 2019 Feb 4;12(1):31. doi: 10.1186/s12920-019-0476-9. BMC Med Genomics. 2019. PMID: 30717762 Free PMC article.
The Impact of Signet Ring Cell Differentiation on Outcome in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma.
van Hootegem SJM, Smithers BM, Gotley DC, Brosda S, Thomson IG, Thomas JM, Gartside M, van Lanschot JJB, Lagarde SM, Wijnhoven BPL, Barbour AP. van Hootegem SJM, et al. Among authors: gartside m. Ann Surg Oncol. 2019 Aug;26(8):2375-2384. doi: 10.1245/s10434-019-07322-x. Epub 2019 Apr 2. Ann Surg Oncol. 2019. PMID: 30941657 Free PMC article.
POLE mutations in families predisposed to cutaneous melanoma.
Aoude LG, Heitzer E, Johansson P, Gartside M, Wadt K, Pritchard AL, Palmer JM, Symmons J, Gerdes AM, Montgomery GW, Martin NG, Tomlinson I, Kearsey S, Hayward NK. Aoude LG, et al. Among authors: gartside m. Fam Cancer. 2015 Dec;14(4):621-8. doi: 10.1007/s10689-015-9826-8. Fam Cancer. 2015. PMID: 26251183
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.
Stark MS, Woods SL, Gartside MG, Bonazzi VF, Dutton-Regester K, Aoude LG, Chow D, Sereduk C, Niemi NM, Tang N, Ellis JJ, Reid J, Zismann V, Tyagi S, Muzny D, Newsham I, Wu Y, Palmer JM, Pollak T, Youngkin D, Brooks BR, Lanagan C, Schmidt CW, Kobe B, MacKeigan JP, Yin H, Brown KM, Gibbs R, Trent J, Hayward NK. Stark MS, et al. Among authors: gartside mg. Nat Genet. 2011 Dec 25;44(2):165-9. doi: 10.1038/ng.1041. Nat Genet. 2011. PMID: 22197930 Free PMC article.
Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma.
Dutton-Regester K, Kakavand H, Aoude LG, Stark MS, Gartside MG, Johansson P, O'Connor L, Lanagan C, Tembe V, Pupo GM, Haydu LE, Schmidt CW, Mann GJ, Thompson JF, Scolyer RA, Hayward NK. Dutton-Regester K, et al. Among authors: gartside mg. Pigment Cell Melanoma Res. 2013 Nov;26(6):852-60. doi: 10.1111/pcmr.12153. Epub 2013 Aug 23. Pigment Cell Melanoma Res. 2013. PMID: 23890154
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