Smith NJ - Search Results

1

Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?

Wilkins BP, Finch AM, Wang Y, Smith NJ. Wilkins BP, et al. Among authors: smith nj. Trends Endocrinol Metab. 2022 Jul;33(7):481-492. doi: 10.1016/j.tem.2022.04.008. Epub 2022 May 10. Trends Endocrinol Metab. 2022. PMID: 35550855 Review.

2

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84.

Montgomery MK, Osborne B, Brandon AE, O'Reilly L, Fiveash CE, Brown SHJ, Wilkins BP, Samsudeen A, Yu J, Devanapalli B, Hertzog A, Tolun AA, Kavanagh T, Cooper AA, Mitchell TW, Biden TJ, Smith NJ, Cooney GJ, Turner N. Montgomery MK, et al. Among authors: smith nj. FASEB J. 2019 Nov;33(11):12264-12276. doi: 10.1096/fj.201900234R. Epub 2019 Aug 15. FASEB J. 2019. PMID: 31415180 Free PMC article.

3

Critically evaluating sweet taste receptor expression and signaling through a molecular pharmacology lens.

Smith NJ, Grant JN, Moon JI, So SS, Finch AM. Smith NJ, et al. FEBS J. 2021 Apr;288(8):2660-2672. doi: 10.1111/febs.15768. Epub 2021 Mar 6. FEBS J. 2021. PMID: 33590961 Free article. Review.

4

Orphan receptor GPR37L1 remains unliganded.

Ngo T, Wilkins BP, So SS, Keov P, Chahal KK, Finch AM, Coleman JLJ, Kufareva I, Smith NJ. Ngo T, et al. Among authors: smith nj. Nat Chem Biol. 2021 Apr;17(4):383-386. doi: 10.1038/s41589-021-00748-z. Epub 2021 Mar 1. Nat Chem Biol. 2021. PMID: 33649602 Free PMC article. No abstract available.

5

Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1.

Mouat MA, Wilkins BP, Ding E, Govindaraju H, Coleman JLJ, Graham RM, Turner N, Smith NJ. Mouat MA, et al. Among authors: smith nj. Cells. 2022 Jun 1;11(11):1814. doi: 10.3390/cells11111814. Cells. 2022. PMID: 35681509 Free PMC article.

6

Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease.

Stavrou MR, So SS, Finch AM, Ballouz S, Smith NJ. Stavrou MR, et al. Among authors: smith nj. Chem Senses. 2023 Jan 1;48:bjad027. doi: 10.1093/chemse/bjad027. Chem Senses. 2023. PMID: 37539767

7

When simple agonism is not enough: emerging modalities of GPCR ligands.

Smith NJ, Bennett KA, Milligan G. Smith NJ, et al. Mol Cell Endocrinol. 2011 Jan 15;331(2):241-7. doi: 10.1016/j.mce.2010.07.009. Epub 2010 Jul 21. Mol Cell Endocrinol. 2011. PMID: 20654693 Review.

8

Identifying ligands at orphan GPCRs: current status using structure-based approaches.

Ngo T, Kufareva I, Coleman JLj, Graham RM, Abagyan R, Smith NJ. Ngo T, et al. Among authors: smith nj. Br J Pharmacol. 2016 Oct;173(20):2934-51. doi: 10.1111/bph.13452. Epub 2016 Mar 5. Br J Pharmacol. 2016. PMID: 26837045 Free PMC article. Review.

9

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

Ngo T, Ilatovskiy AV, Stewart AG, Coleman JL, McRobb FM, Riek RP, Graham RM, Abagyan R, Kufareva I, Smith NJ. Ngo T, et al. Among authors: smith nj. Nat Chem Biol. 2017 Feb;13(2):235-242. doi: 10.1038/nchembio.2266. Epub 2016 Dec 19. Nat Chem Biol. 2017. PMID: 27992882 Free PMC article. Retracted.

10

The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era.

Coleman JL, Ngo T, Smith NJ. Coleman JL, et al. Among authors: smith nj. Cell Signal. 2017 May;33:1-9. doi: 10.1016/j.cellsig.2017.02.004. Epub 2017 Feb 8. Cell Signal. 2017. PMID: 28188824 Review.

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