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MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
Steczina S, Mohran S, Bailey LRJ, McMillen TS, Kooiker KB, Wood NB, Davis J, Previs MJ, Olivotto I, Pioner JM, Geeves MA, Poggesi C, Regnier M. Steczina S, et al. Among authors: mcmillen ts. J Mol Cell Cardiol. 2024 Jun;191:27-39. doi: 10.1016/j.yjmcc.2024.04.010. Epub 2024 Apr 20. J Mol Cell Cardiol. 2024. PMID: 38648963
Raising NAD+ Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.
Walker MA, Chen H, Yadav A, Ritterhoff J, Villet O, McMillen T, Wang Y, Purcell H, Djukovic D, Raftery D, Isoherranen N, Tian R. Walker MA, et al. Among authors: mcmillen t. Circulation. 2023 Dec 19;148(25):2038-2057. doi: 10.1161/CIRCULATIONAHA.123.066039. Epub 2023 Nov 15. Circulation. 2023. PMID: 37965787
Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile.
Dong Q, Lin H, Allen MM, Garneau JR, Sia JK, Smith RC, Haro F, McMillen T, Pope RL, Metcalfe C, Burgo V, Woodson C, Dylla N, Kohout C, Sundararajan A, Snitkin ES, Young VB, Fortier LC, Kamboj M, Pamer EG. Dong Q, et al. Among authors: mcmillen t. Cell Rep. 2023 Aug 29;42(8):112861. doi: 10.1016/j.celrep.2023.112861. Epub 2023 Jul 30. Cell Rep. 2023. PMID: 37523264 Free PMC article.
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.
Kooiker KB, Mohran S, Turner KL, Ma W, Martinson A, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, Irving TC, Geeves MA, Tanner BCW, Regnier M, Davis J, Moussavi-Harami F. Kooiker KB, et al. Among authors: mcmillen ts. Circ Res. 2023 Aug 18;133(5):430-443. doi: 10.1161/CIRCRESAHA.123.322629. Epub 2023 Jul 20. Circ Res. 2023. PMID: 37470183 Free PMC article.
Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle.
Kooiker KB, Mohran S, Turner KL, Ma W, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Martinson A, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, Irving TC, Geeves MA, Tanner BCW, Regnier M, Davis J, Moussavi-Harami F. Kooiker KB, et al. Among authors: mcmillen ts. bioRxiv [Preprint]. 2023 Feb 3:2023.01.31.526380. doi: 10.1101/2023.01.31.526380. bioRxiv. 2023. PMID: 36778318 Free PMC article. Updated. Preprint.
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency.
Bretherton RC, Reichardt IM, Zabrecky KA, Goldstein AJ, Bailey LRJ, Bugg D, McMillen TS, Kooiker KB, Flint GV, Martinson A, Gunaje J, Koser F, Plaster E, Linke WA, Regnier M, Moussavi-Harami F, Sniadecki NJ, DeForest CA, Davis J. Bretherton RC, et al. Among authors: mcmillen ts. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.523684. doi: 10.1101/2023.01.23.523684. bioRxiv. 2023. PMID: 36747691 Free PMC article. Preprint.
Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile.
Dong Q, Lin H, Allen MM, Garneau JR, Sia JK, Smith RC, Haro F, McMillen T, Pope RL, Metcalfe C, Burgo V, Woodson C, Dylla N, Kohout C, Sundararajan A, Snitkin ES, Young VB, Fortier LC, Kamboj M, Pamer EG. Dong Q, et al. Among authors: mcmillen t. bioRxiv [Preprint]. 2023 Jan 12:2023.01.12.523823. doi: 10.1101/2023.01.12.523823. bioRxiv. 2023. PMID: 36711955 Free PMC article. Updated. Preprint.
75 results