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Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma.
Xie Y, Wang Y, Xu Z, Lu Y, Song D, Gao L, Yu D, Li B, Chen G, Zhang H, Feng Q, Zhang Y, Hu K, Huang C, Peng Y, Wu X, Mao Z, Shao J, Zhu W, Shi J. Xie Y, et al. Among authors: huang c. J Biomed Sci. 2022 May 12;29(1):32. doi: 10.1186/s12929-022-00813-2. J Biomed Sci. 2022. PMID: 35546402 Free PMC article. Clinical Trial.
Inhibition of human neutrophil elastase by pentacyclic triterpenes.
Feng L, Liu X, Zhu W, Guo F, Wu Y, Wang R, Chen K, Huang C, Li Y. Feng L, et al. Among authors: huang c. PLoS One. 2013 Dec 20;8(12):e82794. doi: 10.1371/journal.pone.0082794. eCollection 2013. PLoS One. 2013. PMID: 24376583 Free PMC article.
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice.
Feng L, Luo H, Xu Z, Yang Z, Du G, Zhang Y, Yu L, Hu K, Zhu W, Tong Q, Chen K, Guo F, Huang C, Li Y. Feng L, et al. Among authors: huang c. Diabetologia. 2016 Jun;59(6):1276-86. doi: 10.1007/s00125-016-3912-9. Epub 2016 Mar 16. Diabetologia. 2016. PMID: 26983922
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