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Recombineering and MAGE.
Wannier TM, Ciaccia PN, Ellington AD, Filsinger GT, Isaacs FJ, Javanmardi K, Jones MA, Kunjapur AM, Nyerges A, Pal C, Schubert MG, Church GM. Wannier TM, et al. Among authors: church gm. Nat Rev Methods Primers. 2021;1:7. doi: 10.1038/s43586-020-00006-x. Epub 2021 Jan 14. Nat Rev Methods Primers. 2021. PMID: 35540496 Free PMC article.
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.
Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM. Isaacs FJ, et al. Among authors: church gm. Science. 2011 Jul 15;333(6040):348-53. doi: 10.1126/science.1205822. Science. 2011. PMID: 21764749 Free PMC article.
Genome-scale promoter engineering by coselection MAGE.
Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Wang HH, et al. Among authors: church gm. Nat Methods. 2012 Jun;9(6):591-3. doi: 10.1038/nmeth.1971. Epub 2012 Apr 8. Nat Methods. 2012. PMID: 22484848 Free PMC article.
Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: church gm. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Engineering an allosteric transcription factor to respond to new ligands.
Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S. Taylor ND, et al. Among authors: church gm. Nat Methods. 2016 Feb;13(2):177-83. doi: 10.1038/nmeth.3696. Epub 2015 Dec 21. Nat Methods. 2016. PMID: 26689263 Free PMC article.
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli.
Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM. Napolitano MG, et al. Among authors: church gm. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5588-97. doi: 10.1073/pnas.1605856113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601680 Free PMC article.
596 results