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Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker.
Mansurov A, Hosseinchi P, Chang K, Lauterbach AL, Gray LT, Alpar AT, Budina E, Slezak AJ, Kang S, Cao S, Solanki A, Gomes S, Williford JM, Swartz MA, Mendoza JL, Ishihara J, Hubbell JA. Mansurov A, et al. Among authors: hubbell ja. Nat Biomed Eng. 2022 Jul;6(7):819-829. doi: 10.1038/s41551-022-00888-0. Epub 2022 May 9. Nat Biomed Eng. 2022. PMID: 35534574
Materials engineering for immunomodulation.
Hubbell JA, Thomas SN, Swartz MA. Hubbell JA, et al. Nature. 2009 Nov 26;462(7272):449-60. doi: 10.1038/nature08604. Nature. 2009. PMID: 19940915 Review.
Engineering approaches to immunotherapy.
Swartz MA, Hirosue S, Hubbell JA. Swartz MA, et al. Among authors: hubbell ja. Sci Transl Med. 2012 Aug 22;4(148):148rv9. doi: 10.1126/scitranslmed.3003763. Sci Transl Med. 2012. PMID: 22914624 Review.
451 results