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Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway.
Sofi MH, Tian L, Schutt S, Khan I, Choi HJ, Wu Y, Bastian D, Ticer T, Kassir MF, Atilgan FC, Kim J, Sui X, Zivkovic A, Mehrotra S, O'Bryan JP, Stark H, Martin PJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: zivkovic a. Leukemia. 2022 Jul;36(7):1907-1915. doi: 10.1038/s41375-022-01581-6. Epub 2022 May 5. Leukemia. 2022. PMID: 35513703 Free PMC article.
Inhibitors of specific ceramide synthases.
Schiffmann S, Hartmann D, Fuchs S, Birod K, Ferreiròs N, Schreiber Y, Zivkovic A, Geisslinger G, Grösch S, Stark H. Schiffmann S, et al. Among authors: zivkovic a. Biochimie. 2012 Feb;94(2):558-65. doi: 10.1016/j.biochi.2011.09.007. Epub 2011 Sep 17. Biochimie. 2012. PMID: 21945810
FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P(3) and phosphoinositide 3-kinase.
Imeri F, Blanchard O, Jenni A, Schwalm S, Wünsche C, Zivkovic A, Stark H, Pfeilschifter J, Huwiler A. Imeri F, et al. Among authors: zivkovic a. Naunyn Schmiedebergs Arch Pharmacol. 2015 Dec;388(12):1283-92. doi: 10.1007/s00210-015-1159-5. Epub 2015 Aug 13. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26267293 Free article.
Ceramide synthesis regulates T cell activity and GVHD development.
Sofi MH, Heinrichs J, Dany M, Nguyen H, Dai M, Bastian D, Schutt S, Wu Y, Daenthanasanmak A, Gencer S, Zivkovic A, Szulc Z, Stark H, Liu C, Chang YJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: zivkovic a. JCI Insight. 2017 May 18;2(10):e91701. doi: 10.1172/jci.insight.91701. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515365 Free PMC article.
178 results