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A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors.
Fernández-Rodríguez J, Creus-Bachiller E, Zhang X, Martínez-Iniesta M, Ortega-Bertran S, Guha R, Thomas CJ, Wallace MR, Romagosa C, Salazar-Huayna L, Reilly KM, Blakely JO, Serra-Musach J, Pujana MA, Serra E, Villanueva A, Ferrer M, Lázaro C. Fernández-Rodríguez J, et al. Among authors: romagosa c. Mol Cancer Ther. 2022 Jul 5;21(7):1246-1258. doi: 10.1158/1535-7163.MCT-21-0947. Mol Cancer Ther. 2022. PMID: 35511749 Free PMC article.
Analysis of intratumor heterogeneity in Neurofibromatosis type 1 plexiform neurofibromas and neurofibromas with atypical features: Correlating histological and genomic findings.
Carrió M, Gel B, Terribas E, Zucchiatti AC, Moliné T, Rosas I, Teulé Á, Ramón Y Cajal S, López-Gutiérrez JC, Blanco I, Castellanos E, Lázaro C, Stemmer-Rachamimov A, Romagosa C, Serra E. Carrió M, et al. Among authors: romagosa c. Hum Mutat. 2018 Aug;39(8):1112-1125. doi: 10.1002/humu.23552. Epub 2018 May 25. Hum Mutat. 2018. PMID: 29774626
KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors.
Terribas E, Fernández M, Mazuelas H, Fernández-Rodríguez J, Biayna J, Blanco I, Bernal G, Ramos-Oliver I, Thomas C, Guha R, Zhang X, Gel B, Romagosa C, Ferrer M, Lázaro C, Serra E. Terribas E, et al. Among authors: romagosa c. Neurooncol Adv. 2020 Jan 4;2(Suppl 1):i62-i74. doi: 10.1093/noajnl/vdz061. eCollection 2020 Jul. Neurooncol Adv. 2020. PMID: 32642733 Free PMC article.
Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.
Magallón-Lorenz M, Fernández-Rodríguez J, Terribas E, Creus-Batchiller E, Romagosa C, Estival A, Perez Sidelnikova D, Salvador H, Villanueva A, Blanco I, Carrió M, Lázaro C, Serra E, Gel B. Magallón-Lorenz M, et al. Among authors: romagosa c. Hum Genet. 2021 Aug;140(8):1241-1252. doi: 10.1007/s00439-021-02296-x. Epub 2021 May 31. Hum Genet. 2021. PMID: 34059954
Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial.
Martin-Broto J, Lopez-Alvarez M, Moura DS, Ramos R, Collini P, Romagosa C, Bagué S, Renne SL, Barisella M, Velasco V, Coindre JM, Lopez-Lopez D, Dopazo J, Gambarotti M, Braglia L, Merlo DF, Palmerini E, Stacchiotti S, Quagliuolo VL, Lopez-Pousa A, Grignani G, Blay JY, Brunello A, Gutierrez A, Valverde C, Hindi N, Dei Tos AP, Picci P, Casali PG, Gronchi A. Martin-Broto J, et al. Among authors: romagosa c. Mol Cancer Ther. 2021 Dec;20(12):2539-2552. doi: 10.1158/1535-7163.MCT-21-0315. Epub 2021 Sep 22. Mol Cancer Ther. 2021. PMID: 34552008 Clinical Trial.
Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.
Mazuelas H, Magallón-Lorenz M, Fernández-Rodríguez J, Uriarte-Arrazola I, Richaud-Patin Y, Terribas E, Villanueva A, Castellanos E, Blanco I, Raya Á, Chojnacki J, Heyn H, Romagosa C, Lázaro C, Gel B, Carrió M, Serra E. Mazuelas H, et al. Among authors: romagosa c. Cell Rep. 2022 Feb 15;38(7):110385. doi: 10.1016/j.celrep.2022.110385. Cell Rep. 2022. PMID: 35172160 Free article.
Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis.
González-Muñoz T, Di Giannatale A, García-Silva S, Santos V, Sánchez-Redondo S, Savini C, Graña-Castro O, Blanco-Aparicio C, Fischer S, De Wever O, Creus-Bachiller E, Ortega-Bertran S, Pisapia DJ, Rodríguez-Peralto JL, Fernández-Rodríguez J, Pérez-Portabella CR, Alaggio R, Benassi MS, Pazzaglia L, Scotlandi K, Ratner N, Yohay K, Theuer CP, Peinado H. González-Muñoz T, et al. Clin Cancer Res. 2023 Sep 15;29(18):3744-3758. doi: 10.1158/1078-0432.CCR-22-2462. Clin Cancer Res. 2023. PMID: 37432984
BRAF V600E and KRAS G12S mutations in peripheral nerve sheath tumours.
Serrano C, Simonetti S, Hernández-Losa J, Valverde C, Carrato C, Bagué S, Orellana R, Somoza R, Moliné T, Carles J, Huguet P, Romagosa C, Ramón y Cajal S. Serrano C, et al. Among authors: romagosa c. Histopathology. 2013 Feb;62(3):499-504. doi: 10.1111/his.12021. Epub 2012 Nov 27. Histopathology. 2013. PMID: 23190154
A DNA damage repair gene-associated signature predicts responses of patients with advanced soft-tissue sarcoma to treatment with trabectedin.
Moura DS, Peña-Chilet M, Cordero Varela JA, Alvarez-Alegret R, Agra-Pujol C, Izquierdo F, Ramos R, Ortega-Medina L, Martin-Davila F, Castilla-Ramirez C, Hernandez-Leon CN, Romagosa C, Vaz Salgado MA, Lavernia J, Bagué S, Mayodormo-Aranda E, Vicioso L, Hernández Barceló JE, Rubio-Casadevall J, de Juan A, Fiaño-Valverde MC, Hindi N, Lopez-Alvarez M, Lacerenza S, Dopazo J, Gutierrez A, Alvarez R, Valverde C, Martinez-Trufero J, Martín-Broto J. Moura DS, et al. Among authors: romagosa c. Mol Oncol. 2021 Dec;15(12):3691-3705. doi: 10.1002/1878-0261.12996. Epub 2021 Jun 30. Mol Oncol. 2021. PMID: 33983674 Free PMC article.
72 results