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Alpha-1 Antitrypsin Therapy Modifies Neutrophil Adhesion in Patients with Obstructive Lung Disease.
Am J Respir Cell Mol Biol. 2022 Jul;67(1):76-88. doi: 10.1165/rcmb.2021-0433OC.
Am J Respir Cell Mol Biol. 2022.
PMID: 35507773
Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia.
McCarthy C, Dunlea DM, Saldova R, Henry M, Meleady P, McElvaney OJ, Marsh B, Rudd PM, Reeves EP, McElvaney NG.
McCarthy C, et al. Among authors: dunlea dm.
Am J Respir Crit Care Med. 2018 May 15;197(10):1346-1349. doi: 10.1164/rccm.201709-1954LE.
Am J Respir Crit Care Med. 2018.
PMID: 29144158
No abstract available.
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The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals.
Dunlea DM, Fee LT, McEnery T, McElvaney NG, Reeves EP.
Dunlea DM, et al.
J Inflamm Res. 2018 Mar 26;11:123-134. doi: 10.2147/JIR.S156405. eCollection 2018.
J Inflamm Res. 2018.
PMID: 29618937
Free PMC article.
Review.
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Brief Report: Genetic Variation of the α1 -Antitrypsin Gene Is Associated With Increased Autoantibody Production in Rheumatoid Arthritis.
McCarthy C, Orr C, Fee LT, Carroll TP, Dunlea DM, Hunt DJL, Dunne E, O'Connell P, McCarthy G, Kenny D, Fearon U, Veale DJ, Reeves EP, McElvaney NG.
McCarthy C, et al. Among authors: dunlea dm.
Arthritis Rheumatol. 2017 Aug;69(8):1576-1579. doi: 10.1002/art.40127. Epub 2017 Jun 26.
Arthritis Rheumatol. 2017.
PMID: 28409899
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Ataluren, a New Therapeutic for Alpha-1 Antitrypsin-Deficient Individuals with Nonsense Mutations.
Reeves EP, O'Dwyer CA, Dunlea DM, Wormald MR, Hawkins P, Alfares M, Kotton DN, Rowe SM, Wilson AA, McElvaney NG.
Reeves EP, et al. Among authors: dunlea dm.
Am J Respir Crit Care Med. 2018 Oct 15;198(8):1099-1102. doi: 10.1164/rccm.201802-0338LE.
Am J Respir Crit Care Med. 2018.
PMID: 30011228
Free PMC article.
No abstract available.
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Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.
Reeves EP, Dunlea DM, McQuillan K, O'Dwyer CA, Carroll TP, Saldova R, Akepati PR, Wormald MR, McElvaney OJ, Shutchaidat V, Henry M, Meleady P, Keenan J, Liberti DC, Kotton DN, Rudd PM, Wilson AA, McElvaney NG.
Reeves EP, et al. Among authors: dunlea dm.
J Immunol. 2019 Apr 15;202(8):2240-2253. doi: 10.4049/jimmunol.1801045. Epub 2019 Feb 22.
J Immunol. 2019.
PMID: 30796179
Free PMC article.
Clinical Trial.
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Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function.
Reeves EP, McCarthy C, McElvaney OJ, Vijayan MS, White MM, Dunlea DM, Pohl K, Lacey N, McElvaney NG.
Reeves EP, et al. Among authors: dunlea dm.
World J Crit Care Med. 2015 Aug 4;4(3):179-91. doi: 10.5492/wjccm.v4.i3.179. eCollection 2015 Aug 4.
World J Crit Care Med. 2015.
PMID: 26261770
Free PMC article.
Review.
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Characterization of the Inflammatory Response to Severe COVID-19 Illness.
McElvaney OJ, McEvoy NL, McElvaney OF, Carroll TP, Murphy MP, Dunlea DM, Ní Choileáin O, Clarke J, O'Connor E, Hogan G, Ryan D, Sulaiman I, Gunaratnam C, Branagan P, O'Brien ME, Morgan RK, Costello RW, Hurley K, Walsh S, de Barra E, McNally C, McConkey S, Boland F, Galvin S, Kiernan F, O'Rourke J, Dwyer R, Power M, Geoghegan P, Larkin C, O'Leary RA, Freeman J, Gaffney A, Marsh B, Curley GF, McElvaney NG.
McElvaney OJ, et al. Among authors: dunlea dm.
Am J Respir Crit Care Med. 2020 Sep 15;202(6):812-821. doi: 10.1164/rccm.202005-1583OC.
Am J Respir Crit Care Med. 2020.
PMID: 32584597
Free PMC article.
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