Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a.
Xu Y, Jiang YQ, Li C, He M, Rusyniak WG, Annamdevula N, Ochoa J, Leavesley SJ, Xu J, Rich TC, Lin MT, Zha XM.
Xu Y, et al. Among authors: annamdevula n.
FASEB J. 2018 Jul;32(7):3832-3843. doi: 10.1096/fj.201701367R. Epub 2018 Feb 15.
FASEB J. 2018.
PMID: 29447005
Free PMC article.
A single amino acid at position 285 was critical for increased N-glycosylation and surface expression of hASIC1a. Consistent with the changes in trafficking and current, cells expressing hASIC1a or mASIC1a S285P mutant had a higher acid-activated calcium increase and exhib …
A single amino acid at position 285 was critical for increased N-glycosylation and surface expression of hASIC1a. Consistent with the …