Ejeskär K - Search Results

1

Inflammation suppresses DLG2 expression decreasing inflammasome formation.

Keane S, Herring M, Rolny P, Wettergren Y, Ejeskär K. Keane S, et al. Among authors: ejeskar k. J Cancer Res Clin Oncol. 2022 Sep;148(9):2295-2311. doi: 10.1007/s00432-022-04029-7. Epub 2022 May 2. J Cancer Res Clin Oncol. 2022. PMID: 35499706 Free PMC article. Clinical Trial.

2

p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors.

Fransson S, Uv A, Eriksson H, Andersson MK, Wettergren Y, Bergo M, Ejeskär K. Fransson S, et al. Among authors: ejeskar k. Oncogene. 2012 Jul 5;31(27):3277-86. doi: 10.1038/onc.2011.492. Epub 2011 Oct 24. Oncogene. 2012. PMID: 22020336

3

The Unique Non-Catalytic C-Terminus of P37delta-PI3K Adds Proliferative Properties In Vitro and In Vivo.

Ejeskär K, Vickes O, Kuchipudi A, Wettergren Y, Uv A, Rotter Sopasakis V. Ejeskär K, et al. PLoS One. 2015 May 29;10(5):e0127497. doi: 10.1371/journal.pone.0127497. eCollection 2015. PLoS One. 2015. PMID: 26024481 Free PMC article.

4

p110α Hot Spot Mutations E545K and H1047R Exert Metabolic Reprogramming Independently of p110α Kinase Activity.

Chaudhari A, Krumlinde D, Lundqvist A, Akyürek LM, Bandaru S, Skålén K, Ståhlman M, Borén J, Wettergren Y, Ejeskär K, Rotter Sopasakis V. Chaudhari A, et al. Among authors: ejeskar k. Mol Cell Biol. 2015 Oct;35(19):3258-73. doi: 10.1128/MCB.00471-15. Epub 2015 Jul 13. Mol Cell Biol. 2015. PMID: 26169833 Free PMC article.

5

Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity.

Chaudhari A, Ejeskär K, Wettergren Y, Kahn CR, Rotter Sopasakis V. Chaudhari A, et al. Among authors: ejeskar k. F1000Res. 2017 Aug 30;6:1600. doi: 10.12688/f1000research.12418.2. eCollection 2017. F1000Res. 2017. PMID: 29983910 Free PMC article.

6

Low DLG2 gene expression, a link between 11q-deleted and MYCN-amplified neuroblastoma, causes forced cell cycle progression, and predicts poor patient survival.

Keane S, Améen S, Lindlöf A, Ejeskär K. Keane S, et al. Among authors: ejeskar k. Cell Commun Signal. 2020 Apr 20;18(1):65. doi: 10.1186/s12964-020-00553-6. Cell Commun Signal. 2020. PMID: 32312269 Free PMC article.

7

The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma.

Keane S, Martinsson T, Kogner P, Ejeskär K. Keane S, et al. Among authors: ejeskar k. Cancer Cell Int. 2021 Mar 16;21(1):170. doi: 10.1186/s12935-021-01851-w. Cancer Cell Int. 2021. PMID: 33726762 Free PMC article.

8

Discovery of a rare GKAP1-NTRK2 fusion in a pediatric low-grade glioma, leading to targeted treatment with TRK-inhibitor larotrectinib.

Deland L, Keane S, Olsson Bontell T, Sjögren H, Fagman H, Øra I, De La Cuesta E, Tisell M, Nilsson JA, Ejeskär K, Sabel M, Abel F. Deland L, et al. Among authors: ejeskar k. Cancer Biol Ther. 2021 Mar 4;22(3):184-195. doi: 10.1080/15384047.2021.1899573. Epub 2021 Apr 5. Cancer Biol Ther. 2021. PMID: 33820494 Free PMC article.

9

DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma.

Keane S, de Weerd HA, Ejeskär K. Keane S, et al. Among authors: ejeskar k. DNA Repair (Amst). 2022 Apr;112:103302. doi: 10.1016/j.dnarep.2022.103302. Epub 2022 Feb 17. DNA Repair (Amst). 2022. PMID: 35217496 Free article.

10

Novel TPR::ROS1 Fusion Gene Activates MAPK, PI3K and JAK/STAT Signaling in an Infant-type Pediatric Glioma.

Deland L, Keane S, Bontell TO, Fagman H, Sjögren H, Lind AE, Carén H, Tisell M, Nilsson JA, Ejeskär K, Sabel M, Abel F. Deland L, et al. Among authors: ejeskar k. Cancer Genomics Proteomics. 2022 Nov-Dec;19(6):711-726. doi: 10.21873/cgp.20354. Cancer Genomics Proteomics. 2022. PMID: 36316040 Free PMC article.

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