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Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.
Brussee JM, Vet NJ, Krekels EHJ, Valkenburg AJ, Jacqz-Aigrain E, van Gerven JMA, Swart EL, van den Anker JN, Tibboel D, de Hoog M, de Wildt SN, Knibbe CAJ. Brussee JM, et al. Among authors: de wildt sn, de hoog m. Br J Clin Pharmacol. 2018 Feb;84(2):358-368. doi: 10.1111/bcp.13459. Epub 2017 Nov 29. Br J Clin Pharmacol. 2018. PMID: 29072785 Free PMC article.
Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.
Smits A, Annaert P, Cavallaro G, De Cock PAJG, de Wildt SN, Kindblom JM, Lagler FB, Moreno C, Pokorna P, Schreuder MF, Standing JF, Turner MA, Vitiello B, Zhao W, Weingberg AM, Willmann R, van den Anker J, Allegaert K. Smits A, et al. Among authors: de cock pajg, de wildt sn. Br J Clin Pharmacol. 2022 Dec;88(12):4965-4984. doi: 10.1111/bcp.14958. Epub 2021 Jul 23. Br J Clin Pharmacol. 2022. PMID: 34180088 Free PMC article. Review.
General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
Bouazza N, Dokoumetzidis A, Knibbe CAJ, de Wildt SN, Ambery C, De Cock PA, Gasthuys E, Foissac F, Urien S, Hamberg AK, Poggesi I, Zhao W, Vermeulen A, Standing JF, Tréluyer JM; c4c Expert group on Pharmacometrics. Bouazza N, et al. Among authors: de cock pa, de wildt sn. Br J Clin Pharmacol. 2022 Dec;88(12):4985-4996. doi: 10.1111/bcp.15571. Epub 2022 Nov 8. Br J Clin Pharmacol. 2022. PMID: 36256514 Free article. Review.
Clinical, methodology, and patient/carer expert advice in pediatric drug development by conect4children.
Cheng K, Mahler F, Lutsar I, Nafria Escalera B, Breitenstein S, Vassal G, Claverol J, Noel Palacio N, Portman R, Pope G, Bakker M, van der Geest T, Turner MA, de Wildt SN; c4c Expert Group Leads. Cheng K, et al. Among authors: de wildt sn. Clin Transl Sci. 2023 Mar;16(3):478-488. doi: 10.1111/cts.13459. Epub 2022 Dec 12. Clin Transl Sci. 2023. PMID: 36510699 Free PMC article.
245 results