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Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy.
Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, Kohler RH, Sarkaria JN, Parangi S, Sorger PK, Agar NYR, Jacene HA, Sullivan RJ, Buchbinder E, Mikula H, Weissleder R, Miller MA. Ng TSC, et al. Among authors: parangi s. Sci Adv. 2022 Apr 29;8(17):eabl6339. doi: 10.1126/sciadv.abl6339. Epub 2022 Apr 29. Sci Adv. 2022. PMID: 35486732 Free PMC article.
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer.
Li R, Ng TSC, Wang SJ, Prytyskach M, Rodell CB, Mikula H, Kohler RH, Garlin MA, Lauffenburger DA, Parangi S, Dinulescu DM, Bardeesy N, Weissleder R, Miller MA. Li R, et al. Among authors: parangi s. Nat Nanotechnol. 2021 Jul;16(7):830-839. doi: 10.1038/s41565-021-00897-1. Epub 2021 May 6. Nat Nanotechnol. 2021. PMID: 33958764 Free PMC article.
Deciphering albumin-directed drug delivery by imaging.
Hu H, Quintana J, Weissleder R, Parangi S, Miller M. Hu H, et al. Among authors: parangi s. Adv Drug Deliv Rev. 2022 Jun;185:114237. doi: 10.1016/j.addr.2022.114237. Epub 2022 Mar 29. Adv Drug Deliv Rev. 2022. PMID: 35364124 Free PMC article. Review.
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release.
Quintana JM, Arboleda D, Hu H, Scott E, Luthria G, Pai S, Parangi S, Weissleder R, Miller MA. Quintana JM, et al. Among authors: parangi s. Bioconjug Chem. 2022 Aug 17;33(8):1474-1484. doi: 10.1021/acs.bioconjchem.2c00174. Epub 2022 Jul 14. Bioconjug Chem. 2022. PMID: 35833631 Free PMC article.
Detection of Circulating BRAF(V600E) in Patients with Papillary Thyroid Carcinoma.
Lubitz CC, Parangi S, Holm TM, Bernasconi MJ, Schalck AP, Suh H, Economopoulos KP, Gunda V, Donovan SE, Sadow PM, Wirth LJ, Sullivan RJ, Panka DJ. Lubitz CC, et al. Among authors: parangi s. J Mol Diagn. 2016 Jan;18(1):100-8. doi: 10.1016/j.jmoldx.2015.08.003. Epub 2015 Nov 26. J Mol Diagn. 2016. PMID: 26631873 Free PMC article.
136 results