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Regio- and Stereoselective Epoxidation and Acidic Epoxide Opening of Antibacterial and Antiplasmodial Chlorotonils Yield Highly Potent Derivatives.
Hofer W, Oueis E, Fayad AA, Deschner F, Andreas A, de Carvalho LP, Hüttel S, Bernecker S, Pätzold L, Morgenstern B, Zaburannyi N, Bischoff M, Stadler M, Held J, Herrmann J, Müller R. Hofer W, et al. Among authors: de carvalho lp. Angew Chem Int Ed Engl. 2022 Jul 25;61(30):e202202816. doi: 10.1002/anie.202202816. Epub 2022 Jun 13. Angew Chem Int Ed Engl. 2022. PMID: 35485800 Free PMC article.
The toxic effect of Vu-Defr, a defensin from Vigna unguiculata seeds, on Leishmania amazonensis is associated with reactive oxygen species production, mitochondrial dysfunction, and plasma membrane perturbation.
Souza GS, de Carvalho LP, de Melo EJT, Gomes VM, Carvalho AO. Souza GS, et al. Among authors: de melo ejt, de carvalho lp, carvalho ao. Can J Microbiol. 2018 Jul;64(7):455-464. doi: 10.1139/cjm-2018-0095. Epub 2018 Mar 27. Can J Microbiol. 2018. PMID: 29586486
149 results