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CD133 as a Biomarker for an Autoantibody-to-ImmunoPET Paradigm for the Early Detection of Small Cell Lung Cancer.
Kunihiro AG, Sarrett SM, Lastwika KJ, Solan JL, Pisarenko T, Keinänen O, Rodriguez C, Taverne LR, Fitzpatrick AL, Li CI, Houghton AM, Zeglis BM, Lampe PD. Kunihiro AG, et al. Among authors: houghton am. J Nucl Med. 2022 Nov;63(11):1701-1707. doi: 10.2967/jnumed.121.263511. Epub 2022 Apr 28. J Nucl Med. 2022. PMID: 35483965 Free PMC article.
Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules.
Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath SNJ, Randolph TW, Shipley M, Lampe PD, Houghton AM. Lastwika KJ, et al. Among authors: houghton am. Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. doi: 10.1164/rccm.201804-0628OC. Am J Respir Crit Care Med. 2019. PMID: 30422669 Free PMC article.
Prognostic Value of Early Fluorodeoxyglucose-Positron Emission Tomography Response Imaging and Peripheral Immunologic Biomarkers: Substudy of a Phase II Trial of Risk-Adaptive Chemoradiation for Unresectable Non-Small Cell Lung Cancer.
Bowen SR, Hippe DS, Thomas HM, Sasidharan B, Lampe PD, Baik CS, Eaton KD, Lee S, Martins RG, Santana-Davila R, Chen DL, Kinahan PE, Miyaoka RS, Vesselle HJ, Houghton AM, Rengan R, Zeng J. Bowen SR, et al. Among authors: houghton am. Adv Radiat Oncol. 2021 Nov 21;7(2):100857. doi: 10.1016/j.adro.2021.100857. eCollection 2022 Mar-Apr. Adv Radiat Oncol. 2021. PMID: 35387421 Free PMC article.
Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer.
Lastwika KJ, Kunihiro A, Solan JL, Zhang Y, Taverne LR, Shelley D, Rho JH, Randolph TW, Li CI, Grogan EL, Massion PP, Fitzpatrick AL, MacPherson D, Houghton AM, Lampe PD. Lastwika KJ, et al. Among authors: houghton am. Sci Transl Med. 2023 Jan 11;15(678):eadd8469. doi: 10.1126/scitranslmed.add8469. Epub 2023 Jan 11. Sci Transl Med. 2023. PMID: 36630482 Free PMC article.
Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions.
Hiatt JB, Doebley AL, Arnold HU, Adil M, Sandborg H, Persse TW, Ko M, Wu F, Quintanal Villalonga A, Santana-Davila R, Eaton K, Dive C, Rudin CM, Thomas A, Houghton AM, Ha G, MacPherson D. Hiatt JB, et al. Among authors: houghton am. Sci Adv. 2024 Apr 12;10(15):eadk2082. doi: 10.1126/sciadv.adk2082. Epub 2024 Apr 10. Sci Adv. 2024. PMID: 38598634 Free PMC article.
MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Grunblatt E, Wu N, Zhang H, Liu X, Norton JP, Ohol Y, Leger P, Hiatt JB, Eastwood EC, Thomas R, Ibrahim AH, Jia D, Basom R, Eaton KD, Martins R, Houghton AM, MacPherson D. Grunblatt E, et al. Among authors: houghton am. Genes Dev. 2020 Sep 1;34(17-18):1210-1226. doi: 10.1101/gad.340133.120. Epub 2020 Aug 20. Genes Dev. 2020. PMID: 32820040 Free PMC article.
83 results