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Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation.
Nishitani-Isa M, Mukai K, Honda Y, Nihira H, Tanaka T, Shibata H, Kodama K, Hiejima E, Izawa K, Kawasaki Y, Osawa M, Katata Y, Onodera S, Watanabe T, Uchida T, Kure S, Takita J, Ohara O, Saito MK, Nishikomori R, Taguchi T, Sasahara Y, Yasumi T. Nishitani-Isa M, et al. Among authors: mukai k. J Exp Med. 2022 Jun 6;219(6):e20211889. doi: 10.1084/jem.20211889. Epub 2022 Apr 28. J Exp Med. 2022. PMID: 35482294 Free PMC article.
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H. Uchida Y, et al. Among authors: mukai k. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15846-51. doi: 10.1073/pnas.1109101108. Epub 2011 Sep 12. Proc Natl Acad Sci U S A. 2011. PMID: 21911378 Free PMC article.
Activation of STING requires palmitoylation at the Golgi.
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T. Mukai K, et al. Nat Commun. 2016 Jun 21;7:11932. doi: 10.1038/ncomms11932. Nat Commun. 2016. PMID: 27324217 Free PMC article.
STING palmitoylation as a therapeutic target.
Hansen AL, Mukai K, Schopfer FJ, Taguchi T, Holm CK. Hansen AL, et al. Among authors: mukai k. Cell Mol Immunol. 2019 Mar;16(3):236-241. doi: 10.1038/s41423-019-0205-5. Epub 2019 Feb 22. Cell Mol Immunol. 2019. PMID: 30796349 Free PMC article. Review.
Innate immunity signalling and membrane trafficking.
Taguchi T, Mukai K. Taguchi T, et al. Among authors: mukai k. Curr Opin Cell Biol. 2019 Aug;59:1-7. doi: 10.1016/j.ceb.2019.02.002. Epub 2019 Mar 12. Curr Opin Cell Biol. 2019. PMID: 30875551 Free article. Review.
STING Operation at the ER/Golgi Interface.
Taguchi T, Mukai K, Takaya E, Shindo R. Taguchi T, et al. Among authors: mukai k. Front Immunol. 2021 May 3;12:646304. doi: 10.3389/fimmu.2021.646304. eCollection 2021. Front Immunol. 2021. PMID: 34012437 Free PMC article. Review.
1,098 results