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An enhancer sequence in the intrinsically disordered region of FtsZ promotes polymer-guided substrate processing by ClpXP protease.
Protein Sci. 2022 May;31(5):e4306. doi: 10.1002/pro.4306.
Protein Sci. 2022.
PMID: 35481648
Free PMC article.
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads.
Murthy AC, Tang WS, Jovic N, Janke AM, Seo DH, Perdikari TM, Mittal J, Fawzi NL.
Murthy AC, et al. Among authors: perdikari tm.
Nat Struct Mol Biol. 2021 Nov;28(11):923-935. doi: 10.1038/s41594-021-00677-4. Epub 2021 Nov 10.
Nat Struct Mol Biol. 2021.
PMID: 34759379
Free PMC article.
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SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs.
Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL.
Perdikari TM, et al.
EMBO J. 2020 Dec 15;39(24):e106478. doi: 10.15252/embj.2020106478. Epub 2020 Dec 4.
EMBO J. 2020.
PMID: 33200826
Free PMC article.
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A predictive coarse-grained model for position-specific effects of post-translational modifications.
Perdikari TM, Jovic N, Dignon GL, Kim YC, Fawzi NL, Mittal J.
Perdikari TM, et al.
Biophys J. 2021 Apr 6;120(7):1187-1197. doi: 10.1016/j.bpj.2021.01.034. Epub 2021 Feb 12.
Biophys J. 2021.
PMID: 33582133
Free PMC article.
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SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins.
Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL.
Perdikari TM, et al.
bioRxiv [Preprint]. 2020 Jun 10:2020.06.09.141101. doi: 10.1101/2020.06.09.141101.
bioRxiv. 2020.
PMID: 32577653
Free PMC article.
Updated.
Preprint.
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The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation.
Owen I, Yee D, Wyne H, Perdikari TM, Johnson V, Smyth J, Kortum R, Fawzi NL, Shewmaker F.
Owen I, et al. Among authors: perdikari tm.
J Cell Sci. 2021 Sep 1;134(17):jcs258578. doi: 10.1242/jcs.258578. Epub 2021 Sep 3.
J Cell Sci. 2021.
PMID: 34357401
Free PMC article.
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Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
Ryan VH, Perdikari TM, Naik MT, Saueressig CF, Lins J, Dignon GL, Mittal J, Hart AC, Fawzi NL.
Ryan VH, et al. Among authors: perdikari tm.
EMBO J. 2021 Feb 1;40(3):e105001. doi: 10.15252/embj.2020105001. Epub 2020 Dec 22.
EMBO J. 2021.
PMID: 33349959
Free PMC article.
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Motility-limited aggregation of mammary epithelial cells into fractal-like clusters.
Leggett SE, Neronha ZJ, Bhaskar D, Sim JY, Perdikari TM, Wong IY.
Leggett SE, et al. Among authors: perdikari tm.
Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17298-17306. doi: 10.1073/pnas.1905958116. Epub 2019 Aug 14.
Proc Natl Acad Sci U S A. 2019.
PMID: 31413194
Free PMC article.
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