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Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention.
Obesity (Silver Spring). 2022 May;30(5):982-993. doi: 10.1002/oby.23400.
Obesity (Silver Spring). 2022.
PMID: 35470973
Review.
Dysfunctional cerebrovascular tone contributes to cognitive impairment in a non-obese rat model of prediabetic challenge: Role of suppression of autophagy and modulation by anti-diabetic drugs.
Fakih W, Mroueh A, Salah H, Eid AH, Obeid M, Kobeissy F, Darwish H, El-Yazbi AF.
Fakih W, et al.
Biochem Pharmacol. 2020 Aug;178:114041. doi: 10.1016/j.bcp.2020.114041. Epub 2020 May 19.
Biochem Pharmacol. 2020.
PMID: 32439335
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Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay.
Shaito A, Hasan H, Habashy KJ, Fakih W, Abdelhady S, Ahmad F, Zibara K, Eid AH, El-Yazbi AF, Kobeissy FH.
Shaito A, et al. Among authors: fakih w.
EBioMedicine. 2020 Jul;57:102829. doi: 10.1016/j.ebiom.2020.102829. Epub 2020 Jun 20.
EBioMedicine. 2020.
PMID: 32574954
Free PMC article.
Review.
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COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway.
Mroueh A, Fakih W, Carmona A, Trimaille A, Matsushita K, Marchandot B, Qureshi AW, Gong DS, Auger C, Sattler L, Reydel A, Hess S, Oulehri W, Vollmer O, Lessinger JM, Meyer N, Pieper MP, Jesel L, Bäck M, Schini-Kerth V, Morel O.
Mroueh A, et al. Among authors: fakih w.
J Thromb Haemost. 2024 Jan;22(1):286-299. doi: 10.1016/j.jtha.2023.09.022. Epub 2023 Oct 4.
J Thromb Haemost. 2024.
PMID: 37797691
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Activated factor X stimulates atrial endothelial cells and tissues to promote remodeling responses through AT1R/NADPH oxidases/SGLT1/2.
Fakih W, Mroueh A, Gong DS, Kikuchi S, Pieper MP, Kindo M, Mazzucottelli JP, Mommerot A, Kanso M, Ohlmann P, Morel O, Schini-Kerth V, Jesel L.
Fakih W, et al.
Cardiovasc Res. 2024 May 14:cvae101. doi: 10.1093/cvr/cvae101. Online ahead of print.
Cardiovasc Res. 2024.
PMID: 38742661
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