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The Amphiregulin/EGFR axis protects from lupus nephritis via downregulation of pathogenic CD4+ T helper cell responses.
J Autoimmun. 2022 May;129:102829. doi: 10.1016/j.jaut.2022.102829. Epub 2022 Apr 22.
J Autoimmun. 2022.
PMID: 35468361
Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells.
Melderis S, Hagenstein J, Warkotsch MT, Dang J, Herrnstadt GR, Niehus CB, Neumann K, Panzer U, Berasain C, Avila MA, Tharaux PL, Tiegs G, Steinmetz OM.
Melderis S, et al. Among authors: warkotsch mt.
J Am Soc Nephrol. 2020 Sep;31(9):1996-2012. doi: 10.1681/ASN.2019111215. Epub 2020 Jul 2.
J Am Soc Nephrol. 2020.
PMID: 32616537
Free PMC article.
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A Novel Role for IL-6 Receptor Classic Signaling: Induction of RORγt+Foxp3+ Tregs with Enhanced Suppressive Capacity.
Hagenstein J, Melderis S, Nosko A, Warkotsch MT, Richter JV, Ramcke T, Herrnstadt GR, Scheller J, Yan I, Mittrücker HW, Kluger MA, Steinmetz OM.
Hagenstein J, et al. Among authors: warkotsch mt.
J Am Soc Nephrol. 2019 Aug;30(8):1439-1453. doi: 10.1681/ASN.2019020118. Epub 2019 Jul 16.
J Am Soc Nephrol. 2019.
PMID: 31311828
Free PMC article.
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The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis.
Herrnstadt GR, Niehus CB, Ramcke T, Hagenstein J, Ehnold LI, Nosko A, Warkotsch MT, Feindt FC, Melderis S, Paust HJ, Sivayoganathan V, Jauch-Speer SL, Wong MN, Indenbirken D, Krebs CF, Huber TB, Panzer U, Puelles VG, Kluger MA, Steinmetz OM.
Herrnstadt GR, et al. Among authors: warkotsch mt.
Kidney Int. 2023 Jul;104(1):74-89. doi: 10.1016/j.kint.2023.02.027. Epub 2023 Mar 15.
Kidney Int. 2023.
PMID: 36924892
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