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The Amphiregulin/EGFR axis protects from lupus nephritis via downregulation of pathogenic CD4+ T helper cell responses.
Melderis S, Warkotsch MT, Dang J, Hagenstein J, Ehnold LI, Herrnstadt GR, Niehus CB, Feindt FC, Kylies D, Puelles VG, Berasain C, Avila MA, Neumann K, Tiegs G, Huber TB, Tharaux PL, Steinmetz OM. Melderis S, et al. Among authors: tiegs g. J Autoimmun. 2022 May;129:102829. doi: 10.1016/j.jaut.2022.102829. Epub 2022 Apr 22. J Autoimmun. 2022. PMID: 35468361
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Turner JE, Paust HJ, Steinmetz OM, Peters A, Riedel JH, Erhardt A, Wegscheid C, Velden J, Fehr S, Mittrücker HW, Tiegs G, Stahl RA, Panzer U. Turner JE, et al. Among authors: tiegs g. J Am Soc Nephrol. 2010 Jun;21(6):974-85. doi: 10.1681/ASN.2009070741. Epub 2010 Mar 18. J Am Soc Nephrol. 2010. PMID: 20299360 Free PMC article.
Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.
Riedel JH, Paust HJ, Turner JE, Tittel AP, Krebs C, Disteldorf E, Wegscheid C, Tiegs G, Velden J, Mittrücker HW, Garbi N, Stahl RA, Steinmetz OM, Kurts C, Panzer U. Riedel JH, et al. Among authors: tiegs g. J Am Soc Nephrol. 2012 Dec;23(12):1987-2000. doi: 10.1681/ASN.2012040394. Epub 2012 Nov 8. J Am Soc Nephrol. 2012. PMID: 23138484 Free PMC article.
Stat3 programs Th17-specific regulatory T cells to control GN.
Kluger MA, Luig M, Wegscheid C, Goerke B, Paust HJ, Brix SR, Yan I, Mittrücker HW, Hagl B, Renner ED, Tiegs G, Wiech T, Stahl RA, Panzer U, Steinmetz OM. Kluger MA, et al. Among authors: tiegs g. J Am Soc Nephrol. 2014 Jun;25(6):1291-302. doi: 10.1681/ASN.2013080904. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511136 Free PMC article.
Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus.
Kluger MA, Melderis S, Nosko A, Goerke B, Luig M, Meyer MC, Turner JE, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM. Kluger MA, et al. Among authors: tiegs g. Kidney Int. 2016 Jan;89(1):158-66. doi: 10.1038/ki.2015.296. Epub 2016 Jan 4. Kidney Int. 2016. PMID: 26466322 Free article.
CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.
Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U. Paust HJ, et al. Among authors: tiegs g. J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3. J Am Soc Nephrol. 2016. PMID: 26534920 Free PMC article.
187 results