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Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia.
Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, Brennand KJ, Maze I. Farrelly LA, et al. Among authors: shen l. Nat Commun. 2022 Apr 22;13(1):2195. doi: 10.1038/s41467-022-29922-0. Nat Commun. 2022. PMID: 35459277 Free PMC article.
G9a influences neuronal subtype specification in striatum.
Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Daws SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, Schaefer A, Nestler EJ. Maze I, et al. Among authors: shen l. Nat Neurosci. 2014 Apr;17(4):533-9. doi: 10.1038/nn.3670. Epub 2014 Mar 2. Nat Neurosci. 2014. PMID: 24584053 Free PMC article.
β-catenin mediates stress resilience through Dicer1/microRNA regulation.
Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ. Dias C, et al. Among authors: shen l. Nature. 2014 Dec 4;516(7529):51-5. doi: 10.1038/nature13976. Epub 2014 Nov 12. Nature. 2014. PMID: 25383518 Free PMC article.
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD. Maze I, et al. Among authors: shen l. Neuron. 2015 Jul 1;87(1):77-94. doi: 10.1016/j.neuron.2015.06.014. Neuron. 2015. PMID: 26139371 Free PMC article.
ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.
Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, Golden SA, Gleason K, Russo SJ, Andrews S, Neve R, Kennedy PJ, Maze I, Dietz DM, Allis CD, Turecki G, Varga-Weisz P, Tamminga C, Shen L, Nestler EJ. Sun H, et al. Among authors: shen l. Nat Med. 2015 Oct;21(10):1146-53. doi: 10.1038/nm.3939. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390241 Free PMC article.
Erratum to: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens.
Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, Nestler EJ, Shen L. Feng J, et al. Among authors: shen l. Genome Biol. 2015 Oct 14;16:227. doi: 10.1186/s13059-015-0789-8. Genome Biol. 2015. PMID: 26467768 Free PMC article. No abstract available.
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.
Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, Liu X, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ. Bagot RC, et al. Among authors: shen l. Neuron. 2016 Jun 1;90(5):969-83. doi: 10.1016/j.neuron.2016.04.015. Epub 2016 May 12. Neuron. 2016. PMID: 27181059 Free PMC article.
Histone arginine methylation in cocaine action in the nucleus accumbens.
Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, Cates H, Lobo MK, Dietz D, Allis CD, Guccione E, Turecki G, Defilippi P, Neve RL, Hurd YL, Shen L, Nestler EJ. Damez-Werno DM, et al. Among authors: shen l. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9623-8. doi: 10.1073/pnas.1605045113. Epub 2016 Aug 9. Proc Natl Acad Sci U S A. 2016. PMID: 27506785 Free PMC article.
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