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Pan-Phosphodiesterase Inhibitors Attenuate TGF-β-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation.
Wójcik-Pszczoła K, Chłoń-Rzepa G, Jankowska A, Ferreira B, Koczurkiewicz-Adamczyk P, Pękala E, Wyska E, Pociecha K, Gosens R. Wójcik-Pszczoła K, et al. Among authors: pekala e. Pharmaceuticals (Basel). 2022 Mar 30;15(4):423. doi: 10.3390/ph15040423. Pharmaceuticals (Basel). 2022. PMID: 35455420 Free PMC article.
New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K. Chłoń-Rzepa G, et al. Among authors: pekala e. Arch Pharm (Weinheim). 2015 Apr;348(4):242-53. doi: 10.1002/ardp.201500015. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773907
Pentoxifylline and its active metabolite lisofylline attenuate transforming growth factor β1-induced asthmatic bronchial fibroblast-to-myofibroblast transition.
Wójcik-Pszczoła K, Hińcza K, Wnuk D, Kądziołka D, Koczurkiewicz P, Sanak M, Madeja Z, Pękala E, Michalik M. Wójcik-Pszczoła K, et al. Among authors: pekala e. Acta Biochim Pol. 2016;63(3):437-42. doi: 10.18388/abp.2016_1357. Epub 2016 Jul 30. Acta Biochim Pol. 2016. PMID: 27474406 Free article.
Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.
Piska K, Koczurkiewicz P, Bucki A, Wójcik-Pszczoła K, Kołaczkowski M, Pękala E. Piska K, et al. Among authors: pekala e. Invest New Drugs. 2017 Jun;35(3):375-385. doi: 10.1007/s10637-017-0443-2. Epub 2017 Mar 10. Invest New Drugs. 2017. PMID: 28283780 Free PMC article. Review.
Synthesis and Determination of Lipophilicity, Anticonvulsant Activity, and Preliminary Safety of 3-Substituted and 3-Unsubstituted N-[(4-Arylpiperazin-1-yl)alkyl]pyrrolidine-2,5-dione Derivatives.
Rybka S, Obniska J, Żmudzki P, Koczurkiewicz P, Wójcik-Pszczoła K, Pękala E, Bryła A, Rapacz A. Rybka S, et al. Among authors: pekala e. ChemMedChem. 2017 Nov 22;12(22):1848-1856. doi: 10.1002/cmdc.201700539. Epub 2017 Nov 14. ChemMedChem. 2017. PMID: 29045762
122 results