Chłoń-Rzepa G - Search Results

1

Pan-Phosphodiesterase Inhibitors Attenuate TGF-β-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation.

Wójcik-Pszczoła K, Chłoń-Rzepa G, Jankowska A, Ferreira B, Koczurkiewicz-Adamczyk P, Pękala E, Wyska E, Pociecha K, Gosens R. Wójcik-Pszczoła K, et al. Among authors: chlon rzepa g. Pharmaceuticals (Basel). 2022 Mar 30;15(4):423. doi: 10.3390/ph15040423. Pharmaceuticals (Basel). 2022. PMID: 35455420 Free PMC article.

2

New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.

Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K. Chłoń-Rzepa G, et al. Arch Pharm (Weinheim). 2015 Apr;348(4):242-53. doi: 10.1002/ardp.201500015. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773907

3

ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF 8-METHOXY-1,3-DIMETHYL-2,6-DIOXO-PURIN-7-YL DERIVATIVES WITH TERMINAL CARBOXYLIC, ESTER OR AMIDE MOIETIES IN ANIMAL MODELS.

Zygmunt M, Chłon-Rzepa G, Wyska E, Pociecha K, Sapa J. Zygmunt M, et al. Acta Pol Pharm. 2016 May-Jun;73(3):761-70. Acta Pol Pharm. 2016. PMID: 27476295

4

PDE7-Selective and Dual Inhibitors: Advances in Chemical and Biological Research.

Jankowska A, Swierczek A, Chlon-Rzepa G, Pawlowski M, Wyska E. Jankowska A, et al. Curr Med Chem. 2017;24(7):673-700. doi: 10.2174/0929867324666170116125159. Curr Med Chem. 2017. PMID: 28093982 Review.

5

Multi-Target-Directed Ligands Affecting Serotonergic Neurotransmission for Alzheimer's Disease Therapy: Advances in Chemical and Biological Research.

Jankowska A, Wesolowska A, Pawlowski M, Chlon-Rzepa G. Jankowska A, et al. Curr Med Chem. 2018;25(17):2045-2067. doi: 10.2174/0929867324666170529122802. Curr Med Chem. 2018. PMID: 28554324 Review.

6

In Vitro Biotransformation, Safety, and Chemopreventive Action of Novel 8-Methoxy-Purine-2,6-Dione Derivatives.

Marć MA, Domínguez-Álvarez E, Słoczyńska K, Żmudzki P, Chłoń-Rzepa G, Pękala E. Marć MA, et al. Appl Biochem Biotechnol. 2018 Jan;184(1):124-139. doi: 10.1007/s12010-017-2527-z. Epub 2017 Jun 17. Appl Biochem Biotechnol. 2018. PMID: 28624999 Free PMC article.

7

Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation.

Chłoń-Rzepa G, Jankowska A, Ślusarczyk M, Świerczek A, Pociecha K, Wyska E, Bucki A, Gawalska A, Kołaczkowski M, Pawłowski M. Chłoń-Rzepa G, et al. Eur J Med Chem. 2018 Feb 25;146:381-394. doi: 10.1016/j.ejmech.2018.01.068. Epub 2018 Feb 4. Eur J Med Chem. 2018. PMID: 29407965

8

STUDIES OF NEW PURINE DERIVATIVES WITH ACETIC ACID MOIETY IN HUMAN KERATINOCYTES.

Wojcik-Pszczola K, Stalinska J, Koczurkiewicz P, Chlon-Rzepa G, Drukala J, Wyszkowska-Kolatko M, Pekala E. Wojcik-Pszczola K, et al. Acta Pol Pharm. 2017 Jan;74(1):111-117. Acta Pol Pharm. 2017. PMID: 29474767 Free article.

9

Advances in Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 1: Overview of the Chemical and Biological Research.

Jankowska A, Świerczek A, Wyska E, Gawalska A, Bucki A, Pawłowski M, Chłoń-Rzepa G. Jankowska A, et al. Curr Drug Targets. 2019;20(1):122-143. doi: 10.2174/1389450119666180808105056. Curr Drug Targets. 2019. PMID: 30091414 Review.

10

Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.

Chłoń-Rzepa G, Ślusarczyk M, Jankowska A, Gawalska A, Bucki A, Kołaczkowski M, Świerczek A, Pociecha K, Wyska E, Zygmunt M, Kazek G, Sałat K, Pawłowski M. Chłoń-Rzepa G, et al. Eur J Med Chem. 2018 Oct 5;158:517-533. doi: 10.1016/j.ejmech.2018.09.021. Epub 2018 Sep 10. Eur J Med Chem. 2018. PMID: 30245393

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