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Page 1
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. de Vries LE, et al. Among authors: verhoef jmj. Nat Commun. 2022 Apr 20;13(1):2158. doi: 10.1038/s41467-022-29688-5. Nat Commun. 2022. PMID: 35444200 Free PMC article.
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, Wittlin S, Scheurer C, Sax S, Fischli C, Angulo-Barturen I, Jiménez-Diaz MB, Josling G, Kooij TWA, Bonnert R, Campo B, Blaauw RH, Rutjes FPJT, Sauerwein RW, Llinás M, Hermkens PHH, Dechering KJ. Schalkwijk J, et al. Among authors: verhoef jmj. Sci Transl Med. 2019 Sep 18;11(510):eaas9917. doi: 10.1126/scitranslmed.aas9917. Sci Transl Med. 2019. PMID: 31534021
Organelle Dynamics in Apicomplexan Parasites.
Verhoef JMJ, Meissner M, Kooij TWA. Verhoef JMJ, et al. mBio. 2021 Aug 31;12(4):e0140921. doi: 10.1128/mBio.01409-21. Epub 2021 Aug 24. mBio. 2021. PMID: 34425697 Free PMC article. Review.
Detailing organelle division and segregation in Plasmodium falciparum.
Verhoef JMJ, Boshoven C, Evers F, Akkerman LJ, Gijsbrechts BCA, van de Vegte-Bolmer M, van Gemert GJ, Vaidya AB, Kooij TWA. Verhoef JMJ, et al. bioRxiv [Preprint]. 2024 May 13:2024.01.30.577899. doi: 10.1101/2024.01.30.577899. bioRxiv. 2024. PMID: 38352445 Free PMC article. Preprint.
MAM 2024: Malaria in a changing world.
Longley RJ, Malinga J, Hesping E, Sutanto E, DonVito SM, Kucharski M, Oyong DA, Verhoef JMJ, Du E, Villasis E, Mwikali K. Longley RJ, et al. Among authors: verhoef jmj. Trends Parasitol. 2024 May;40(5):355-361. doi: 10.1016/j.pt.2024.03.007. Epub 2024 Apr 12. Trends Parasitol. 2024. PMID: 38609740 No abstract available.