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Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Guidi R, Xu D, Choy DF, Ramalingam TR, Lee WP, Modrusan Z, Liang Y, Marsters S, Ashkenazi A, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Leong L, Cook A, Tran TH, Austin CD, Cao Y, Clarke C, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Wang F, Wilson MS. Guidi R, et al. Among authors: clarke c. Sci Transl Med. 2022 Apr 20;14(641):eabl8146. doi: 10.1126/scitranslmed.abl8146. Epub 2022 Apr 20. Sci Transl Med. 2022. PMID: 35442706 Free PMC article.
Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection.
Entwistle L, Aegerter H, Czieso S, Amaniti E, Guidi R, Sesay A, Nikolov N, Chakravaty P, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Cao Y, Clarke C, Martzall A, Leong L, Wilson D, Austin C, Wilson M. Entwistle L, et al. Among authors: clarke c. Mucosal Immunol. 2021 Jul;14(4):912-922. doi: 10.1038/s41385-021-00401-x. Epub 2021 Apr 12. Mucosal Immunol. 2021. PMID: 33846533 Free PMC article.
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. Headland SE, et al. Among authors: clarke c. Sci Transl Med. 2022 Jan 12;14(627):eabf8188. doi: 10.1126/scitranslmed.abf8188. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020406
Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration.
Orozco LD, Chen HH, Cox C, Katschke KJ Jr, Arceo R, Espiritu C, Caplazi P, Nghiem SS, Chen YJ, Modrusan Z, Dressen A, Goldstein LD, Clarke C, Bhangale T, Yaspan B, Jeanne M, Townsend MJ, van Lookeren Campagne M, Hackney JA. Orozco LD, et al. Among authors: clarke c. Cell Rep. 2020 Jan 28;30(4):1246-1259.e6. doi: 10.1016/j.celrep.2019.12.082. Cell Rep. 2020. PMID: 31995762 Free article.
A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration.
Orozco LD, Owen LA, Hofmann J, Stockwell AD, Tao J, Haller S, Mukundan VT, Clarke C, Lund J, Sridhar A, Mayba O, Barr JL, Zavala RA, Graves EC, Zhang C, Husami N, Finley R, Au E, Lillvis JH, Farkas MH, Shakoor A, Sherva R, Kim IK, Kaminker JS, Townsend MJ, Farrer LA, Yaspan BL, Chen HH, DeAngelis MM. Orozco LD, et al. Among authors: clarke c. Cell Genom. 2023 Apr 18;3(6):100302. doi: 10.1016/j.xgen.2023.100302. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388919 Free PMC article.
Chemotherapy-free treatment targeting fusions and driver mutations in KRAS wild-type pancreatic ductal adenocarcinoma, a case series.
Mehdi M, Szabo A, Shreenivas A, Thomas JP, Tsai S, Christians KK, Evans DB, Clarke CN, Hall WA, Erickson B, Ahmed G, Thapa B, McFall T, George B, Kurzrock R, Kamgar M. Mehdi M, et al. Among authors: clarke cn. Ther Adv Med Oncol. 2024 May 19;16:17588359241253113. doi: 10.1177/17588359241253113. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 38770091 Free PMC article.
Concentration-Dependent Effects of Curcumin on Membrane Permeability and Structure.
Gudyka J, Ceja-Vega J, Ivanchenko K, Morocho Z, Panella M, Gamez Hernandez A, Clarke C, Perez E, Silverberg S, Lee S. Gudyka J, et al. Among authors: clarke c. ACS Pharmacol Transl Sci. 2024 Apr 10;7(5):1546-1556. doi: 10.1021/acsptsci.4c00093. eCollection 2024 May 10. ACS Pharmacol Transl Sci. 2024. PMID: 38751632
Anion-Dependent Strength Scale of Interactions in Ionic Liquids from X-ray Photoelectron Spectroscopy, Ab Initio Molecular Dynamics, and Density Functional Theory.
Gousseva E, Towers Tompkins FK, Seymour JM, Parker LG, Clarke CJ, Palgrave RG, Bennett RA, Grau-Crespo R, Lovelock KRJ. Gousseva E, et al. Among authors: clarke cj. J Phys Chem B. 2024 May 23;128(20):5030-5043. doi: 10.1021/acs.jpcb.4c00362. Epub 2024 May 10. J Phys Chem B. 2024. PMID: 38727250
2,795 results