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Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Guidi R, Xu D, Choy DF, Ramalingam TR, Lee WP, Modrusan Z, Liang Y, Marsters S, Ashkenazi A, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Leong L, Cook A, Tran TH, Austin CD, Cao Y, Clarke C, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Wang F, Wilson MS. Guidi R, et al. Among authors: ashkenazi a. Sci Transl Med. 2022 Apr 20;14(641):eabl8146. doi: 10.1126/scitranslmed.abl8146. Epub 2022 Apr 20. Sci Transl Med. 2022. PMID: 35442706 Free PMC article.
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. Harnoss JM, et al. Among authors: ashkenazi a. Cancer Res. 2020 Jun 1;80(11):2368-2379. doi: 10.1158/0008-5472.CAN-19-3108. Epub 2020 Apr 7. Cancer Res. 2020. PMID: 32265225 Free PMC article.
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.
Xi Y, LaCanna R, Ma HY, N'Diaye EN, Gierke S, Caplazi P, Sagolla M, Huang Z, Lucio L, Arlantico A, Jeet S, Brightbill H, Emson C, Wong A, Morshead KB, DePianto DJ, Roose-Girma M, Yu C, Tam L, Jia G, Ramalingam TR, Marsters S, Ashkenazi A, Kim SH, Kelly R, Wu S, Wolters PJ, Feldstein AE, Vander Heiden JA, Ding N. Xi Y, et al. Among authors: ashkenazi a. Cell Metab. 2022 Sep 6;34(9):1377-1393.e8. doi: 10.1016/j.cmet.2022.07.009. Epub 2022 Aug 19. Cell Metab. 2022. PMID: 35987202 Free article.
TRAF2 is a biologically important necroptosis suppressor.
Petersen SL, Chen TT, Lawrence DA, Marsters SA, Gonzalvez F, Ashkenazi A. Petersen SL, et al. Among authors: ashkenazi a. Cell Death Differ. 2015 Nov;22(11):1846-57. doi: 10.1038/cdd.2015.35. Epub 2015 Apr 17. Cell Death Differ. 2015. PMID: 25882049 Free PMC article.
554 results