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Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.
Ham DJ, Börsch A, Chojnowska K, Lin S, Leuchtmann AB, Ham AS, Thürkauf M, Delezie J, Furrer R, Burri D, Sinnreich M, Handschin C, Tintignac LA, Zavolan M, Mittal N, Rüegg MA. Ham DJ, et al. Among authors: handschin c. Nat Commun. 2022 Apr 19;13(1):2025. doi: 10.1038/s41467-022-29714-6. Nat Commun. 2022. PMID: 35440545 Free PMC article.
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA. Romanino K, et al. Among authors: handschin c. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20808-13. doi: 10.1073/pnas.1111448109. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143799 Free PMC article.
154 results