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Crosstalk between invadopodia and the extracellular matrix.
Iizuka S, Leon RP, Gribbin KP, Zhang Y, Navarro J, Smith R, Devlin K, Wang LG, Gibbs SL, Korkola J, Nan X, Courtneidge SA. Iizuka S, et al. Among authors: courtneidge sa. Eur J Cell Biol. 2020 Sep;99(7):151122. doi: 10.1016/j.ejcb.2020.151122. Epub 2020 Sep 15. Eur J Cell Biol. 2020. PMID: 33070041
Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.
Iizuka S, Quintavalle M, Navarro JC, Gribbin KP, Ardecky RJ, Abelman MM, Ma CT, Sergienko E, Zeng FY, Pass I, Thomas GV, McWeeney SK, Hassig CA, Pinkerton AB, Courtneidge SA. Iizuka S, et al. Among authors: courtneidge sa. Cancer Res. 2021 Mar 15;81(6):1472-1485. doi: 10.1158/0008-5472.CAN-20-2383. Epub 2021 Jan 7. Cancer Res. 2021. PMID: 33414172 Free PMC article.
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.
Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH. Gast CE, et al. Among authors: courtneidge sa. Sci Adv. 2018 Sep 12;4(9):eaat7828. doi: 10.1126/sciadv.aat7828. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30214939 Free PMC article.
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.
Leong HS, Robertson AE, Stoletov K, Leith SJ, Chin CA, Chien AE, Hague MN, Ablack A, Carmine-Simmen K, McPherson VA, Postenka CO, Turley EA, Courtneidge SA, Chambers AF, Lewis JD. Leong HS, et al. Among authors: courtneidge sa. Cell Rep. 2014 Sep 11;8(5):1558-70. doi: 10.1016/j.celrep.2014.07.050. Epub 2014 Aug 28. Cell Rep. 2014. PMID: 25176655 Free article.
128 results