Toren P - Search Results

1

Simultaneous quantification of trimethoprim metabolites in pediatric plasma.

Tessman RT, Nolte W, Toren P, Gibson K, Vu L, Goldman J. Tessman RT, et al. Among authors: toren p. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 May 15;1198:123232. doi: 10.1016/j.jchromb.2022.123232. Epub 2022 Apr 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35428009 Free PMC article.

2

Quantification of a dual angiotensin I-converting enzyme-neutral endopeptidase inhibitor and the active thiol metabolite in dog plasma by high-performance liquid chromatography with ultraviolet absorbance detection.

Heath TG, Massad DD, Carroll JI, Mathews BS, Chang J, Scott DO, Kuo BS, Toren PC. Heath TG, et al. Among authors: toren pc. J Chromatogr B Biomed Appl. 1995 Aug 4;670(1):91-101. doi: 10.1016/0378-4347(95)00134-5. J Chromatogr B Biomed Appl. 1995. PMID: 7493089

3

Disposition and metabolism of rifapentine, a rifamycin antibiotic, in mice, rats, and monkeys.

Emary WB, Toren PC, Mathews B, Huh K. Emary WB, et al. Among authors: toren pc. Drug Metab Dispos. 1998 Aug;26(8):725-31. Drug Metab Dispos. 1998. PMID: 9698285

4

Disposition and metabolism of 14C-rifapentine in healthy volunteers.

Reith K, Keung A, Toren PC, Cheng L, Eller MG, Weir SJ. Reith K, et al. Among authors: toren pc. Drug Metab Dispos. 1998 Aug;26(8):732-8. Drug Metab Dispos. 1998. PMID: 9698286

5

The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.

Chapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JS. Chapron BD, et al. Drug Metab Dispos. 2020 Nov;48(11):1113-1120. doi: 10.1124/dmd.120.000188. Epub 2020 Aug 26. Drug Metab Dispos. 2020. PMID: 32847865 Free PMC article.

6

High-resolution mass spectrometry elucidates metabonate (false metabolite) formation from alkylamine drugs during in vitro metabolite profiling.

Barbara JE, Kazmi F, Muranjan S, Toren PC, Parkinson A. Barbara JE, et al. Drug Metab Dispos. 2012 Oct;40(10):1966-75. doi: 10.1124/dmd.112.047027. Epub 2012 Jul 13. Drug Metab Dispos. 2012. PMID: 22798552

7

Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions.

Ogilvie BW, Zhang D, Li W, Rodrigues AD, Gipson AE, Holsapple J, Toren P, Parkinson A. Ogilvie BW, et al. Among authors: toren p. Drug Metab Dispos. 2006 Jan;34(1):191-7. doi: 10.1124/dmd.105.007633. Epub 2005 Nov 18. Drug Metab Dispos. 2006. PMID: 16299161

8

Determination of interchain crosslinkages in insulin B-chain dimers by fast atom bombardment mass spectrometry.

Toren P, Smith D, Chance R, Hoffman J. Toren P, et al. Anal Biochem. 1988 Mar;169(2):287-99. doi: 10.1016/0003-2697(88)90287-4. Anal Biochem. 1988. PMID: 3289414

9

The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel.

Ogilvie BW, Yerino P, Kazmi F, Buckley DB, Rostami-Hodjegan A, Paris BL, Toren P, Parkinson A. Ogilvie BW, et al. Among authors: toren p. Drug Metab Dispos. 2011 Nov;39(11):2020-33. doi: 10.1124/dmd.111.041293. Epub 2011 Jul 27. Drug Metab Dispos. 2011. PMID: 21795468

10

An evaluation of the dilution method for identifying metabolism-dependent inhibitors of cytochrome P450 enzymes.

Parkinson A, Kazmi F, Buckley DB, Yerino P, Paris BL, Holsapple J, Toren P, Otradovec SM, Ogilvie BW. Parkinson A, et al. Among authors: toren p. Drug Metab Dispos. 2011 Aug;39(8):1370-87. doi: 10.1124/dmd.111.038596. Epub 2011 Apr 27. Drug Metab Dispos. 2011. PMID: 21525169

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