Shearer J - Search Results

1

Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):182-200. doi: 10.1177/10915818221077225. Epub 2022 Apr 15. Int J Toxicol. 2022. PMID: 35426748

2

Reproductive and developmental toxicology studies of iminosugar UV-4.

Shearer J, Wolfe G, Khaliq M, Kaufman B, Sampath A, Warfield KL, Ramstedt U, Treston A. Shearer J, et al. Reprod Toxicol. 2022 Dec;114:9-21. doi: 10.1016/j.reprotox.2022.09.007. Epub 2022 Oct 4. Reprod Toxicol. 2022. PMID: 36206921 Free article.

3

Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):201-211. doi: 10.1177/10915818211072842. Epub 2022 Feb 28. Int J Toxicol. 2022. PMID: 35227115 Free PMC article.

4

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Shearer JD, Saylor ML, Butler CM, Treston AM, Heine HS, Chirakul S, Schweizer HP, Louie A, Drusano GL, Zumbrun SD, Warfield KL. Shearer JD, et al. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e00834-19. doi: 10.1128/AAC.00834-19. Epub 2019 Sep 23. Antimicrob Agents Chemother. 2019. PMID: 31548183 Free PMC article.

5

Repeat-Dose Toxicity Study of a Lyophilized Recombinant Protective Antigen-Based Anthrax Vaccine Adjuvanted With CpG 7909.

Savransky V, Lacy M, Ionin B, Skiadopoulos MH, Shearer J. Savransky V, et al. Among authors: shearer j. Int J Toxicol. 2019 May/Jun;38(3):163-172. doi: 10.1177/1091581819848722. Int J Toxicol. 2019. PMID: 31179828

6

Repeat Dose Toxicity Study of the AV7909 Anthrax Vaccine Candidate in Juvenile Rats.

Zmarowski A, Ballin JD, Sharits J, Carrico K, Novak J, Shearer J, Blauth B, Ionin B, Reece J, Savransky V. Zmarowski A, et al. Among authors: shearer j. Int J Toxicol. 2020 Jul 21:1091581820941412. doi: 10.1177/1091581820941412. Online ahead of print. Int J Toxicol. 2020. PMID: 32691648

7

Preclinical safety assessment of a recombinant plague vaccine (rF1V).

Price JL, Manetz TS, Shearer JD, House RV. Price JL, et al. Int J Toxicol. 2013 Sep-Oct;32(5):327-35. doi: 10.1177/1091581813497405. Epub 2013 Aug 1. Int J Toxicol. 2013. PMID: 23908395

8

Developmental and reproductive safety evaluation of AV7909 anthrax vaccine candidate in rats.

Mylchreest E, Smiley MA, Ballin JD, Blauth B, Shearer J, Reece J, Ionin B, Savransky V. Mylchreest E, et al. Among authors: shearer j. Birth Defects Res. 2021 Jan 1;113(1):32-42. doi: 10.1002/bdr2.1815. Epub 2020 Oct 16. Birth Defects Res. 2021. PMID: 33067910 Free PMC article.

9

Comparative immunogenicity and efficacy of thermostable (lyophilized) and liquid formulation of anthrax vaccine candidate AV7909.

Autumn Smiley M, Sanford DC, Triplett CA, Callahan D, Frolov V, Look J, Ruiz C, Reece JJ, Miles A, Ruiz E, Ionin B, Shearer JD, Savransky V. Autumn Smiley M, et al. Among authors: shearer jd. Vaccine. 2019 Oct 8;37(43):6356-6361. doi: 10.1016/j.vaccine.2019.09.015. Epub 2019 Sep 14. Vaccine. 2019. PMID: 31530467 Free PMC article.

10

Development of a guinea pig inhalational anthrax model for evaluation of post-exposure prophylaxis efficacy of anthrax vaccines.

Perry MR, Ionin B, Barnewall RE, Vassar ML, Reece JJ, Park S, Lemiale L, Skiadopoulos MH, Shearer JD, Savransky V. Perry MR, et al. Among authors: shearer jd. Vaccine. 2020 Feb 28;38(10):2307-2314. doi: 10.1016/j.vaccine.2020.01.068. Epub 2020 Feb 3. Vaccine. 2020. PMID: 32029323 Free PMC article.

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