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Effect of cardioplegic arrest and reperfusion on left and right ventricular proteome/phosphoproteome in patients undergoing surgery for coronary or aortic valve disease.
Abdul-Ghani S, Skeffington KL, Kim M, Moscarelli M, Lewis PA, Heesom K, Fiorentino F, Emanueli C, Reeves BC, Punjabi PP, Angelini GD, Suleiman MS. Abdul-Ghani S, et al. Among authors: heesom k. Int J Mol Med. 2022 Jun;49(6):77. doi: 10.3892/ijmm.2022.5133. Epub 2022 Apr 15. Int J Mol Med. 2022. PMID: 35425992 Free PMC article.
Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury.
Littlejohns B, Pasdois P, Duggan S, Bond AR, Heesom K, Jackson CL, Angelini GD, Halestrap AP, Suleiman MS. Littlejohns B, et al. Among authors: heesom k. PLoS One. 2014 Jun 20;9(6):e100579. doi: 10.1371/journal.pone.0100579. eCollection 2014. PLoS One. 2014. PMID: 24950187 Free PMC article.
Changes in contractile protein expression are linked to ventricular stiffness in infants with pulmonary hypertension or right ventricular hypertrophy due to congenital heart disease.
Bond AR, Iacobazzi D, Abdul-Ghani S, Ghorbel M, Heesom K, Wilson M, Gillett C, George SJ, Caputo M, Suleiman S, Tulloh RMR. Bond AR, et al. Among authors: heesom k. Open Heart. 2018 Jan 3;5(1):e000716. doi: 10.1136/openhrt-2017-000716. eCollection 2018. Open Heart. 2018. PMID: 29344379 Free PMC article.
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.
Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA. Carrat GR, et al. Among authors: heesom kj. Mol Metab. 2020 Oct;40:101015. doi: 10.1016/j.molmet.2020.101015. Epub 2020 May 13. Mol Metab. 2020. PMID: 32416313 Free PMC article.
A role for NPY-NPY2R signaling in albuminuric kidney disease.
Lay AC, Barrington AF, Hurcombe JA, Ramnath RD, Graham M, Lewis PA, Wilson MC, Heesom KJ, Butler MJ, Perrett RM, Neal CR, Herbert E, Mountjoy E, Atan D, Nair V, Ju W, Nelson RG, Kretzler M, Satchell SC, McArdle CA, Welsh GI, Coward RJM. Lay AC, et al. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15862-15873. doi: 10.1073/pnas.2004651117. Epub 2020 Jun 19. Proc Natl Acad Sci U S A. 2020. PMID: 32561647 Free PMC article.
154 results