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Evolutionary adaptation of the protein folding pathway for secretability.
Smets D, Tsirigotaki A, Smit JH, Krishnamurthy S, Portaliou AG, Vorobieva A, Vranken W, Karamanou S, Economou A. Smets D, et al. Among authors: vorobieva a. EMBO J. 2022 Dec 1;41(23):e111344. doi: 10.15252/embj.2022111344. Epub 2022 Aug 29. EMBO J. 2022. PMID: 36031863 Free PMC article.
De novo design of transmembrane β barrels.
Vorobieva AA, White P, Liang B, Horne JE, Bera AK, Chow CM, Gerben S, Marx S, Kang A, Stiving AQ, Harvey SR, Marx DC, Khan GN, Fleming KG, Wysocki VH, Brockwell DJ, Tamm LK, Radford SE, Baker D. Vorobieva AA, et al. Science. 2021 Feb 19;371(6531):eabc8182. doi: 10.1126/science.abc8182. Science. 2021. PMID: 33602829 Free PMC article.
De novo design of a fluorescence-activating β-barrel.
Dou J, Vorobieva AA, Sheffler W, Doyle LA, Park H, Bick MJ, Mao B, Foight GW, Lee MY, Gagnon LA, Carter L, Sankaran B, Ovchinnikov S, Marcos E, Huang PS, Vaughan JC, Stoddard BL, Baker D. Dou J, et al. Among authors: vorobieva aa. Nature. 2018 Sep;561(7724):485-491. doi: 10.1038/s41586-018-0509-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209393 Free PMC article.
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins.
Klima JC, Doyle LA, Lee JD, Rappleye M, Gagnon LA, Lee MY, Barros EP, Vorobieva AA, Dou J, Bremner S, Quon JS, Chow CM, Carter L, Mack DL, Amaro RE, Vaughan JC, Berndt A, Stoddard BL, Baker D. Klima JC, et al. Among authors: vorobieva aa. Nat Commun. 2021 Feb 8;12(1):856. doi: 10.1038/s41467-020-18911-w. Nat Commun. 2021. PMID: 33558528 Free PMC article.
19 results