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Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics.
Iida T, Mizutani Y, Esaki N, Ponik SM, Burkel BM, Weng L, Kuwata K, Masamune A, Ishihara S, Haga H, Kataoka K, Mii S, Shiraki Y, Ishikawa T, Ohno E, Kawashima H, Hirooka Y, Fujishiro M, Takahashi M, Enomoto A. Iida T, et al. Among authors: ponik sm. Oncogene. 2022 May;41(19):2764-2777. doi: 10.1038/s41388-022-02288-9. Epub 2022 Apr 13. Oncogene. 2022. PMID: 35414659
Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells.
Morris BA, Burkel B, Ponik SM, Fan J, Condeelis JS, Aguirre-Ghiso JA, Castracane J, Denu JM, Keely PJ. Morris BA, et al. Among authors: ponik sm. EBioMedicine. 2016 Nov;13:146-156. doi: 10.1016/j.ebiom.2016.10.012. Epub 2016 Oct 8. EBioMedicine. 2016. PMID: 27743905 Free PMC article.
Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
Mizutani Y, Kobayashi H, Iida T, Asai N, Masamune A, Hara A, Esaki N, Ushida K, Mii S, Shiraki Y, Ando K, Weng L, Ishihara S, Ponik SM, Conklin MW, Haga H, Nagasaka A, Miyata T, Matsuyama M, Kobayashi T, Fujii T, Yamada S, Yamaguchi J, Wang T, Woods SL, Worthley D, Shimamura T, Fujishiro M, Hirooka Y, Enomoto A, Takahashi M. Mizutani Y, et al. Among authors: ponik sm. Cancer Res. 2019 Oct 15;79(20):5367-5381. doi: 10.1158/0008-5472.CAN-19-0454. Epub 2019 Aug 22. Cancer Res. 2019. PMID: 31439548
Effect of matrix heterogeneity on cell mechanosensing.
Proestaki M, Burkel BM, Galles EE, Ponik SM, Notbohm J. Proestaki M, et al. Among authors: ponik sm. Soft Matter. 2021 Nov 24;17(45):10263-10273. doi: 10.1039/d1sm00312g. Soft Matter. 2021. PMID: 34125129 Free PMC article.
56 results