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Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism.
Nat Med. 2022 Apr;28(4):752-765. doi: 10.1038/s41591-022-01749-8. Epub 2022 Apr 11.
Nat Med. 2022.
PMID: 35411077
Free PMC article.
Brain Microenvironment Heterogeneity: Potential Value for Brain Tumors.
Álvaro-Espinosa L, de Pablos-Aragoneses A, Valiente M, Priego N.
Álvaro-Espinosa L, et al.
Front Oncol. 2021 Sep 1;11:714428. doi: 10.3389/fonc.2021.714428. eCollection 2021.
Front Oncol. 2021.
PMID: 34540682
Free PMC article.
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A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.
Zhu L, Retana D, García-Gómez P, Álvaro-Espinosa L, Priego N, Masmudi-Martín M, Yebra N, Miarka L, Hernández-Encinas E, Blanco-Aparicio C, Martínez S, Sobrino C, Ajenjo N, Artiga MJ, Ortega-Paino E, Torres-Ruiz R, Rodríguez-Perales S; RENACER; Soffietti R, Bertero L, Cassoni P, Weiss T, Muñoz J, Sepúlveda JM, González-León P, Jiménez-Roldán L, Moreno LM, Esteban O, Pérez-Núñez Á, Hernández-Laín A, Toldos O, Ruano Y, Alcázar L, Blasco G, Fernández-Alén J, Caleiras E, Lafarga M, Megías D, Graña-Castro O, Nör C, Taylor MD, Young LS, Varešlija D, Cosgrove N, Couch FJ, Cussó L, Desco M, Mouron S, Quintela-Fandino M, Weller M, Pastor J, Valiente M.
Zhu L, et al. Among authors: alvaro espinosa l.
EMBO Mol Med. 2022 Mar 7;14(3):e14552. doi: 10.15252/emmm.202114552. Epub 2022 Feb 17.
EMBO Mol Med. 2022.
PMID: 35174975
Free PMC article.
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Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits.
Sanchez-Aguilera A, Masmudi-Martín M, Navas-Olive A, Baena P, Hernández-Oliver C, Priego N, Cordón-Barris L, Alvaro-Espinosa L, García S, Martínez S, Lafarga M; RENACER; Lin MZ, Al-Shahrour F, Menendez de la Prida L, Valiente M.
Sanchez-Aguilera A, et al. Among authors: alvaro espinosa l.
Cancer Cell. 2023 Sep 11;41(9):1637-1649.e11. doi: 10.1016/j.ccell.2023.07.010. Epub 2023 Aug 30.
Cancer Cell. 2023.
PMID: 37652007
Free PMC article.
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Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity.
Santos CP, Lapi E, Martínez de Villarreal J, Álvaro-Espinosa L, Fernández-Barral A, Barbáchano A, Domínguez O, Laughney AM, Megías D, Muñoz A, Real FX.
Santos CP, et al. Among authors: alvaro espinosa l.
Nat Commun. 2019 Sep 27;10(1):4407. doi: 10.1038/s41467-019-12307-1.
Nat Commun. 2019.
PMID: 31562298
Free PMC article.
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Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer.
Raymant M, Astuti Y, Alvaro-Espinosa L, Green D, Quaranta V, Bellomo G, Glenn M, Chandran-Gorner V, Palmer DH, Halloran C, Ghaneh P, Henderson NC, Morton JP, Valiente M, Mielgo A, Schmid MC.
Raymant M, et al. Among authors: alvaro espinosa l.
Nat Commun. 2024 Apr 27;15(1):3593. doi: 10.1038/s41467-024-47949-3.
Nat Commun. 2024.
PMID: 38678021
Free PMC article.
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