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Elimination of Off-Target Effect by Chemical Modification of 5'-End of siRNA.
Shiohama Y, Fujita R, Sonokawa M, Hisano M, Kotake Y, Krstic-Demonacos M, Demonacos C, Kashiwazaki G, Kitayama T, Fujii M. Shiohama Y, et al. Among authors: kotake y. Nucleic Acid Ther. 2022 Oct;32(5):438-447. doi: 10.1089/nat.2021.0068. Epub 2022 Apr 11. Nucleic Acid Ther. 2022. PMID: 35404139
Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.
Diala I, Shiohama Y, Fujita T, Kotake Y, Demonacos C, Krstic-Demonacos M, Leva GD, Fujii M. Diala I, et al. Among authors: kotake y. Nucleosides Nucleotides Nucleic Acids. 2020;39(1-3):407-425. doi: 10.1080/15257770.2020.1713357. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 32310030
423 results