Di Stefano G - Search Results

1

Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme.

Iacovino LG, Rossi M, Di Stefano G, Rossi V, Binda C, Brigotti M, Tomaselli F, Pasti AP, Dal Piaz F, Cerini S, Hochkoeppler A. Iacovino LG, et al. Among authors: di stefano g. Biochimie. 2022 Aug;199:23-35. doi: 10.1016/j.biochi.2022.03.008. Epub 2022 Apr 7. Biochimie. 2022. PMID: 35398441

2

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

Manerba M, Vettraino M, Fiume L, Di Stefano G, Sartini A, Giacomini E, Buonfiglio R, Roberti M, Recanatini M. Manerba M, et al. Among authors: di stefano g. ChemMedChem. 2012 Feb 6;7(2):311-7. doi: 10.1002/cmdc.201100471. Epub 2011 Nov 4. ChemMedChem. 2012. PMID: 22052811

3

Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells.

Fiume L, Vettraino M, Carnicelli D, Arfilli V, Di Stefano G, Brigotti M. Fiume L, et al. Among authors: di stefano g. Biochem Biophys Res Commun. 2013 Jan 11;430(2):466-9. doi: 10.1016/j.bbrc.2012.12.013. Epub 2012 Dec 10. Biochem Biophys Res Commun. 2013. PMID: 23237800

4

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

Vettraino M, Manerba M, Govoni M, Di Stefano G. Vettraino M, et al. Among authors: di stefano g. Anticancer Drugs. 2013 Sep;24(8):862-70. doi: 10.1097/CAD.0b013e328363ae50. Anticancer Drugs. 2013. PMID: 23797802

5

Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.

Manerba M, Di Ianni L, Govoni M, Roberti M, Recanatini M, Di Stefano G. Manerba M, et al. Among authors: di stefano g, di ianni l. Eur J Pharm Sci. 2017 Jan 1;96:37-44. doi: 10.1016/j.ejps.2016.09.014. Epub 2016 Sep 10. Eur J Pharm Sci. 2017. PMID: 27622920

6

Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment.

Balboni A, Govoni M, Rossi V, Roberti M, Cavalli A, Di Stefano G, Manerba M. Balboni A, et al. Among authors: di stefano g. Biochim Biophys Acta Gen Subj. 2021 Jan;1865(1):129760. doi: 10.1016/j.bbagen.2020.129760. Epub 2020 Oct 7. Biochim Biophys Acta Gen Subj. 2021. PMID: 33035602

7

Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin.

Govoni M, Rossi V, Di Stefano G, Manerba M. Govoni M, et al. Among authors: di stefano g. Pathol Oncol Res. 2021 Dec 20;27:1609951. doi: 10.3389/pore.2021.1609951. eCollection 2021. Pathol Oncol Res. 2021. PMID: 34987311 Free PMC article.

8

Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme.

Pasti AP, Rossi V, Di Stefano G, Brigotti M, Hochkoeppler A. Pasti AP, et al. Among authors: di stefano g. Biosci Rep. 2022 Jan 28;42(1):BSR20212654. doi: 10.1042/BSR20212654. Biosci Rep. 2022. PMID: 35048959 Free PMC article.

9

Lactate is a potential promoter of tamoxifen resistance in MCF7 cells.

Rossi V, Govoni M, Farabegoli F, Di Stefano G. Rossi V, et al. Among authors: di stefano g. Biochim Biophys Acta Gen Subj. 2022 Sep;1866(9):130185. doi: 10.1016/j.bbagen.2022.130185. Epub 2022 Jun 3. Biochim Biophys Acta Gen Subj. 2022. PMID: 35661802

10

Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug's Oxidative Damage on Cardiomyocytes.

Rossi V, Govoni M, Di Stefano G. Rossi V, et al. Among authors: di stefano g. Cancers (Basel). 2023 Jul 22;15(14):3728. doi: 10.3390/cancers15143728. Cancers (Basel). 2023. PMID: 37509389 Free PMC article.

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