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Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia.
Campostrini G, Kosmidis G, Ward-van Oostwaard D, Davis RP, Yiangou L, Ottaviani D, Veerman CC, Mei H, Orlova VV, Wilde AAM, Bezzina CR, Verkerk AO, Mummery CL, Bellin M. Campostrini G, et al. Among authors: bellin m. Cardiovasc Res. 2023 Mar 17;119(1):167-182. doi: 10.1093/cvr/cvac059. Cardiovasc Res. 2023. PMID: 35394010 Free PMC article.
Induced pluripotent stem cells: the new patient?
Bellin M, Marchetto MC, Gage FH, Mummery CL. Bellin M, et al. Nat Rev Mol Cell Biol. 2012 Nov;13(11):713-26. doi: 10.1038/nrm3448. Epub 2012 Oct 4. Nat Rev Mol Cell Biol. 2012. PMID: 23034453 Review.
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
Zhang M, D'Aniello C, Verkerk AO, Wrobel E, Frank S, Ward-van Oostwaard D, Piccini I, Freund C, Rao J, Seebohm G, Atsma DE, Schulze-Bahr E, Mummery CL, Greber B, Bellin M. Zhang M, et al. Among authors: bellin m. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5383-92. doi: 10.1073/pnas.1419553111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453094 Free PMC article.
Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology.
Ribeiro MC, Tertoolen LG, Guadix JA, Bellin M, Kosmidis G, D'Aniello C, Monshouwer-Kloots J, Goumans MJ, Wang YL, Feinberg AW, Mummery CL, Passier R. Ribeiro MC, et al. Among authors: bellin m. Biomaterials. 2015 May;51:138-150. doi: 10.1016/j.biomaterials.2015.01.067. Epub 2015 Feb 18. Biomaterials. 2015. PMID: 25771005
Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure.
Kosmidis G, Bellin M, Ribeiro MC, van Meer B, Ward-van Oostwaard D, Passier R, Tertoolen LG, Mummery CL, Casini S. Kosmidis G, et al. Among authors: bellin m. Biochem Biophys Res Commun. 2015 Nov 27;467(4):998-1005. doi: 10.1016/j.bbrc.2015.10.026. Epub 2015 Oct 9. Biochem Biophys Res Commun. 2015. PMID: 26456652
545 results