Wu WJ - Search Results

1

Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.

Maestre-Reyna M, Yang CH, Nango E, Huang WC, Ngurah Putu EPG, Wu WJ, Wang PH, Franz-Badur S, Saft M, Emmerich HJ, Wu HY, Lee CC, Huang KF, Chang YK, Liao JH, Weng JH, Gad W, Chang CW, Pang AH, Sugahara M, Owada S, Hosokawa Y, Joti Y, Yamashita A, Tanaka R, Tanaka T, Luo F, Tono K, Hsu KC, Kiontke S, Schapiro I, Spadaccini R, Royant A, Yamamoto J, Iwata S, Essen LO, Bessho Y, Tsai MD. Maestre-Reyna M, et al. Among authors: wu hy, wu wj. Nat Chem. 2022 Jun;14(6):677-685. doi: 10.1038/s41557-022-00922-3. Epub 2022 Apr 7. Nat Chem. 2022. PMID: 35393554

2

Structural insights into RbmA, a biofilm scaffolding protein of V. cholerae.

Maestre-Reyna M, Wu WJ, Wang AH. Maestre-Reyna M, et al. Among authors: wu wj. PLoS One. 2013 Dec 5;8(12):e82458. doi: 10.1371/journal.pone.0082458. eCollection 2013. PLoS One. 2013. PMID: 24340031 Free PMC article.

3

How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.

Wu WJ, Su MI, Wu JL, Kumar S, Lim LH, Wang CW, Nelissen FH, Chen MC, Doreleijers JF, Wijmenga SS, Tsai MD. Wu WJ, et al. Among authors: wu jl. J Am Chem Soc. 2014 Apr 2;136(13):4927-37. doi: 10.1021/ja4102375. Epub 2014 Mar 21. J Am Chem Soc. 2014. PMID: 24617852

4

Structural Mechanism for the Fidelity Modulation of DNA Polymerase λ.

Liu MS, Tsai HY, Liu XX, Ho MC, Wu WJ, Tsai MD. Liu MS, et al. Among authors: wu wj. J Am Chem Soc. 2016 Feb 24;138(7):2389-98. doi: 10.1021/jacs.5b13368. Epub 2016 Feb 11. J Am Chem Soc. 2016. PMID: 26836966 Free article.

5

Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation.

Chen ES, Weng JH, Chen YH, Wang SC, Liu XX, Huang WC, Matsui T, Kawano Y, Liao JH, Lim LH, Bessho Y, Huang KF, Wu WJ, Tsai MD. Chen ES, et al. Among authors: wu wj. Biochemistry. 2017 Sep 26;56(38):5112-5124. doi: 10.1021/acs.biochem.7b00689. Epub 2017 Sep 15. Biochemistry. 2017. PMID: 28858528

6

Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn²⁺-Mediated Functions.

Chang YK, Huang YP, Liu XX, Ko TP, Bessho Y, Kawano Y, Maestre-Reyna M, Wu WJ, Tsai MD. Chang YK, et al. Among authors: wu wj. J Am Chem Soc. 2019 May 29;141(21):8489-8502. doi: 10.1021/jacs.9b01741. Epub 2019 May 17. J Am Chem Soc. 2019. PMID: 31067051 Free article.

7

Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.

LinWu SW, Tu YH, Tsai TY, Maestre-Reyna M, Liu MS, Wu WJ, Huang JY, Chi HW, Chang WH, Chiou CF, Wang AH, Lee J, Tsai MD. LinWu SW, et al. Among authors: wu wj. Commun Biol. 2019 Jun 20;2:224. doi: 10.1038/s42003-019-0458-7. eCollection 2019. Commun Biol. 2019. PMID: 31240262 Free PMC article.

8

Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors.

Hsieh IS, Gopula B, Chou CC, Wu HY, Chang GD, Wu WJ, Chang CS, Chu PC, Chen CS. Hsieh IS, et al. Among authors: wu hy, wu wj. J Med Chem. 2019 Sep 26;62(18):8497-8510. doi: 10.1021/acs.jmedchem.9b00763. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31465224

9

Vibrio cholerae biofilm scaffolding protein RbmA shows an intrinsic, phosphate-dependent autoproteolysis activity.

Maestre-Reyna M, Huang WC, Wu WJ, Singh PK, Hartmann R, Wang PH, Lee CC, Hikima T, Yamamoto M, Bessho Y, Drescher K, Tsai MD, Wang AH. Maestre-Reyna M, et al. Among authors: wu wj. IUBMB Life. 2021 Feb;73(2):418-431. doi: 10.1002/iub.2439. Epub 2020 Dec 28. IUBMB Life. 2021. PMID: 33372380 Free PMC article.

10

Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.

Luo SC, Yeh HY, Lan WH, Wu YM, Yang CH, Chang HY, Su GC, Lee CY, Wu WJ, Li HW, Ho MC, Chi P, Tsai MD. Luo SC, et al. Among authors: wu ym, wu wj. Nat Commun. 2021 Jan 14;12(1):115. doi: 10.1038/s41467-020-20258-1. Nat Commun. 2021. PMID: 33446654 Free PMC article.

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